PMID: 8957334Sep 1, 1996Paper

Psoralen plus UVA protocol for Compositae photosensitivity

American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society
D A BurkeF J Storrs

Abstract

Patients allergic to sesquiterpene lactones found in Compositae plants may develop severe photosensitivity, which can result in persistent light reaction. Treatment of these exquisitely photosensitive individuals can be very difficult, often requiring hospitalization. Although some treatment regimens have used psoralen plus UVA (PUVA) therapy, no specific outpatient protocol has been established The purpose of this study was to develop an effective PUVA outpatient regimen to treat compositae photosensitivity. A prednisone-assisted PUVA protocol was established in which the prednisone does was decreased weekly, and the PUVA dose was increased during the same time interval. Both patients enrolled in the study experienced dramatic improvement in their previously unresponsive eruptions. Two men aged 66 and 80 years were subjected to this protocol. Both men had chronic photodistributed dermatitis that resolved with this treatment and in one instance has remained clear for 18 months without needing further PUVA therapy.

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Citations

Jul 1, 1997·Clinics in Dermatology·C R Lovell
Jun 10, 2003·Medicinski pregled·Marina Jovanović, Mirjana Poljacki
Jul 28, 2013·Leukemia & Lymphoma·Mari YoshiharaShinya Kimura
Nov 28, 2012·The Annals of Thoracic Surgery·Tsutomu MatsushitaYoshiaki Imamura
Feb 26, 2010·Korean Circulation Journal·Sung Woo ChoYoung Jin Yuh
Dec 14, 2012·Korean Circulation Journal·Sung Woo ChoYoung Sup Byun
May 15, 2013·Dermatitis : Contact, Atopic, Occupational, Drug·Tiffany KwokJoel G DeKoven

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