Psoriasis Flares Following Systemic Glucocorticoid Exposure in Patients With a History of Psoriasis.

JAMA Dermatology
Anna R F GregoireErik J Stratman

Abstract

To our knowledge, this study is the first to assess the rate of any type of psoriasis flare during or immediately following the administration of systemic corticosteroids in patients with a known history of psoriasis. To determine the rates and types of psoriasis flares during or within 3 months after concluding systemic corticosteroid administration in adult patients with a known history of psoriasis. This retrospective cohort study assessed adult patients (≥18 years at the time of psoriasis diagnosis) evaluated in the Marshfield Clinic Health System (Marshfield, Wisconsin) with an established diagnosis of psoriasis and exposure to at least 1 systemic corticosteroid from October 31, 2012, to July 1, 2018. Exclusion criteria were patients younger than 18 years, patients with a diagnosis of psoriatic arthritis, and patients receiving only topical, intraarticular, or intrabursal corticosteroids. The primary outcome was rate of psoriasis flares during or within 3 months of discontinuation of the patient's first course of systemic corticosteroids. Secondary measures included rates of specific types of psoriasis flares, including pustular, erythrodermic, and worsening plaque stage psoriasis. Of 516 cohort patients, 288 (55.8%) were ...Continue Reading

References

May 8, 2014·Journal of Cutaneous Medicine and Surgery·Amir Al-DabaghSteven R Feldman
Oct 21, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·A NastN Yawalkar
Jul 17, 2016·Journal of Cutaneous Medicine and Surgery·UNKNOWN Canadian Psoriasis Guidelines Addendum Committee

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Citations

Jun 12, 2021·Journal of the American Academy of Dermatology·Hideaki MiyachiHideo Yasunaga
Jun 18, 2021·Psoriasis : Targets and Therapy·Yang Lo, Tsen-Fang Tsai
Sep 16, 2021·JAAD Case Reports·Danielle PernaCourtney R Schadt

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