PspC, a pneumococcal surface protein, binds human factor H

Infection and Immunity
Sandhya DaveLarry S McDaniel

Abstract

PspC was found to bind human complement factor H (FH) by Western blot analysis of D39 (pspC(+)) and an isogenic mutant TRE108 (pspC). We confirmed that PspA does not bind FH, while purified PspC binds FH very strongly. The binding of FH to exponentially growing pneumococci varied among different isolates when analyzed by fluorescence activated cell sorting analysis.

References

Feb 1, 1987·The Journal of Experimental Medicine·Larry S McDanielDavid E Briles
Aug 24, 1999·Infection and Immunity·A H TuAlexander J Szalai
Jul 29, 2000·The Journal of Infectious Diseases·B L Smith, M K Hostetter

Citations

Nov 19, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S ShomaA van Belkum
Oct 17, 2012·Journal of Clinical Immunology·Zsóka WeiszhárIldikó Horváth
Aug 14, 2003·Molecular Immunology·Hanna JarvaSeppo Meri
Dec 7, 2002·The Lancet Infectious Diseases·Uwe KoedelHans-Walter Pfister
Mar 24, 2004·Nature Reviews. Microbiology·Timothy J Mitchell
May 28, 2010·The Journal of Biological Chemistry·Vaibhav AgarwalSven Hammerschmidt
Jul 18, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ravi MaruvadaC E Rubens
Jun 4, 2011·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Daniel P MillerRichard T Marconi
Jul 8, 2011·Clinical Microbiology Reviews·Barry B Mook-KanamoriDiederik van de Beek
Jan 18, 2005·Clinical Microbiology Reviews·Gunnar LindahlThomas Areschoug
May 8, 2013·Infection and Immunity·Mirian DomenechJose Yuste
Mar 3, 2010·Infection and Immunity·Merit MelinMerja Väkeväinen
Jan 14, 2009·Infection and Immunity·Vishakha SabharwalStephen I Pelton
Sep 13, 2001·Infection and Immunity·Abiodun David OgunniyiJames C Paton
Oct 16, 2002·Infection and Immunity·Vinod PandiripallyDavid Cue
Apr 23, 2004·Infection and Immunity·Francesco IannelliGianni Pozzi
Jan 25, 2005·Infection and Immunity·Ravichandran PalaniappanJames W Lillard
Apr 23, 2005·Infection and Immunity·Daniela PrachtSven Hammerschmidt
Dec 22, 2005·Infection and Immunity·Daphne WareEdwin Swiatlo
Apr 24, 2007·Journal of Bacteriology·Megumi F MillsLarry S McDaniel
Jul 14, 2010·BMC Microbiology·Cécile FroletAnne Marie Di Guilmi
Jul 7, 2011·PloS One·Gabriella De AngelisMichèle A Barocchi
Sep 7, 2013·The Journal of Infectious Diseases·Sarah BrowallBirgitta Henriques-Normark
Jul 9, 2014·Annual Review of Microbiology·Cheryl Y M Okumura, Victor Nizet
Jul 13, 2014·International Journal of Pediatric Otorhinolaryngology·Patricia A SchachernSteven K Juhn
Dec 28, 2012·Cellular and Molecular Life Sciences : CMLS·Eliane N MiyajiPaulo L Ho
Jul 24, 2012·Trends in Microbiology·Charles D PlumptreJames C Paton
Jun 28, 2011·Advanced Drug Delivery Reviews·Maria V Carroll, Robert B Sim
Aug 25, 2009·Molecular Immunology·Maria V CarrollRobert B Sim
Sep 26, 2015·Annual Review of Genetics·Florian DouamAlexander Ploss
Dec 13, 2005·Current Opinion in Microbiology·Sven Hammerschmidt
Jul 14, 2005·Molecular Immunology·Peter Kraiczy, Reinhard Würzner
May 8, 2015·Environmental Microbiology Reports·Mirian DomenechErnesto García
May 6, 2016·Frontiers in Cellular and Infection Microbiology·Sandy M WongBrian J Akerley
Jul 31, 2013·Critical Reviews in Microbiology·Michelle DarrieuxLuciana Cezar de Cerqueira Leite
Nov 22, 2014·Frontiers in Cellular and Infection Microbiology·Ryan P Gilley, Carlos J Orihuela
Feb 18, 2009·FEMS Immunology and Medical Microbiology·Lauren B KingLarry S McDaniel
Jun 10, 2010·FEMS Immunology and Medical Microbiology·In-Hwa YooUn-Hwan Ha
Aug 6, 2003·FEMS Immunology and Medical Microbiology·Edwin Swiatlo, Daphne Ware
Mar 16, 2007·FEMS Microbiology Letters·Xiangyun He, Larry S McDaniel
Oct 6, 2006·FEMS Microbiology Letters·Lisa R QuinLarry S McDaniel
Feb 6, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A M Mitchell, T J Mitchell
May 9, 2014·Clinical and Vaccine Immunology : CVI·Cintia F M VadesilhoEliane N Miyaji
Nov 2, 2005·The Journal of Biological Chemistry·Peter W M HermansSven Hammerschmidt
Apr 7, 2006·The Journal of Biological Chemistry·Ling LuJing-Ren Zhang
Oct 19, 2019·Vaccines·Victor MoraisNorma Suarez
Jan 29, 2002·The Journal of Biological Chemistry·Thomas AreschougGunnar Lindahl
Oct 31, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Abiodun David OgunniyiJames C Paton
Sep 19, 2003·The Journal of Biological Chemistry·Ling LuJing-Ren Zhang
Jun 6, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Antoine Dieudonné-VatranBarbara Albiger
Aug 29, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Vaibhav AgarwalAnna M Blom
Jun 21, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Teresia HallströmKristian Riesbeck
Oct 16, 2015·The Journal of Immunology : Official Journal of the American Association of Immunologists·Andrew P HerbertPaul N Barlow
Jun 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sandhya DaveLarry S McDaniel
Feb 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Hanna JarvaSeppo Meri
Aug 22, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Anja KunertPeter F Zipfel
Nov 5, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ling LuJing-Ren Zhang
Jul 19, 2013·The Journal of Immunology : Official Journal of the American Association of Immunologists·Hanne AmdahlT Sakari Jokiranta
Feb 2, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Hanna JarvaSeppo Meri
Jul 23, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Charlotta SandinGunnar Lindahl
Feb 18, 2017·Applied Biochemistry and Biotechnology·Ana Paula Corrêa ArgondizzoMarco Alberto Medeiros
Aug 6, 2019·Frontiers in Microbiology·Faye C MorrisAnton Y Peleg
Apr 20, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sven HammerschmidtPeter F Zipfel
Jun 6, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Muriel C SchneiderChristoph M Tang
Mar 1, 2014·Emerging Microbes & Infections·Xiaolei PanJing-Ren Zhang
Mar 8, 2017·Frontiers in Microbiology·Greiciely O AndreMichelle Darrieux
Jan 27, 2006·Microbiology·Kim S LeMessurierJames C Paton

Related Concepts

Pneumococcal surface protein A
Calcium-binding protein 1, Dictyostelium discoideum
SpsA protein, Streptococcus pneumoniae
Complement factor H, human
Bacterial Proteins
Calcium-Binding Proteins
Western Blot
Protozoan Proteins
Complement FACTOR H

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