pspK gene prevalence and characterization of non-typable Streptococcus pneumonia isolates from Asian countries

Microbiology
In Young NaKwan Soo Ko

Abstract

Recently, it has been reported that some non-typable (NT) Streptococcus pneumoniae isolates from Korea and other countries contained a novel gene pspK in the capsular polysaccharide synthesis (cps) locus. In this study, we investigated the presence of pspK in 120 NT S. pneumoniae isolates from 12 Asian countries; isolate characteristics were also examined. The presence of pspK was assayed by PCR. Clonality of NT S. pneumoniae isolates containing pspK was investigated by MLST and PFGE. Antimicrobial susceptibility testing was performed and the structure of pspK was also determined. Nineteen NT isolates (15.8 %) were identified as containing pspK: two isolates from Korea, four from Vietnam, two from Hong Kong, eight from Thailand, and one each from Taiwan, the Philippines and Saudi Arabia. Seven isolates from Korea, Vietnam and Thailand were identified as ST1106, whereas just one or two belonged to ST310, ST393, ST10137, ST2754 or ST4136. All but one of the ST1106 NT isolates showed non-susceptibility to penicillin, and all isolates were resistant to cefuroxime, erythromycin, clindamycin and trimethoprim/sulfamethoxazole. The structure of pspK was similar amongst 20 isolates, which had a R1-R2-like region and a variable number of...Continue Reading

References

Jun 4, 2004·Journal of Bacteriology·Lucy J HathawayKathrin Mühlemann
Jun 30, 2005·FEMS Immunology and Medical Microbiology·Kwan Soo KoJae-Hoon Song
Aug 20, 2005·Journal of Bacteriology·William P HanageBrian G Spratt
Feb 3, 2007·Journal of Clinical Microbiology·In Ho ParkMoon H Nahm
Apr 26, 2007·FEMS Immunology and Medical Microbiology·Chinwendu OnwubikoLarry S McDaniel
Jan 1, 2010·Journal of Clinical Microbiology·R MarshA J Leach
Jan 22, 2011·Diagnostic Microbiology and Infectious Disease·Qingfu XuMichael E Pichichero

❮ Previous
Next ❯

Citations

Mar 24, 2016·MBio·Lance E KellerLarry S McDaniel
Jun 27, 2019·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Noriko TakeuchiNaruhiko Ishiwada
Mar 7, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Mitsuyo KawaguchiyaNobumichi Kobayashi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Related Papers

Japanese Journal of Infectious Diseases
Bin ChangHaruo Watanabe
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Jayakayatri Jeevajothi NathanNiazlin Mohd Taib
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
L SombreroARIVAC consortium
© 2022 Meta ULC. All rights reserved