PMID: 9425796Jan 13, 1998Paper

Psychiatric disorders in women: psychopharmacologic treatments

Journal of the American Pharmaceutical Association : APhA
M P Fankhauser

Abstract

To review the most common psychiatric disorders in women and to address gender-related pharmacokinetic and pharmacodynamic differences in psychotropic medications. Recent clinical literature selected by the author. Women have higher prevalence rates of anxiety, mood, and eating disorders than do men, and they are prescribed the majority of psychotropic medications. In general, women experience more comorbid illnesses, have a higher rate of morbidity and disability, and suffer more from reversible drug-induced or medically induced psychiatric conditions. Biological factors such as hormonal and neurotransmitter fluctuations during the menstrual cycle, pregnancy, postpartum, perimenopause, and postmenopause may affect the pharmacokinetics of psychotropic medications. Information is needed about gender differences in the incidence and diagnosis of psychiatric disorders; sex differences in the treatment, response, pharmacokinetics, and adverse effects of psychotropic medications; and safety of psychotropic medications in the fetus and in the breast-fed infant. An understanding of the impact of physiologic, hormonal, and neurotransmitter changes associated with different life phases should provide valuable insight into the treatment ...Continue Reading

Citations

Feb 5, 2013·CNS Spectrums·Donatella MarazzitiLiliana Dell'Osso
Jul 30, 2005·The Australian and New Zealand Journal of Psychiatry·Caryl Barnes, Philip Mitchell
Aug 19, 2009·Pharmacoepidemiology and Drug Safety·J H A Van der HeydenJ Tafforeau

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