PMID: 6146153Jan 1, 1984

Psycho-social stress, insomnia and temazepam: a sleep laboratory evaluation in a "general practice" sample

M D BearyA V Bhat


Taking a population of women most of whom were about to seek medication from their general practitioner for stress-induced insomnia, this sleep laboratory study examined--both electro -physiologically and psychologically--the immediate impact of temazepam, at normal prescribed dosage, on sleep. The study was double-blind, controlled with random allocation. Temazepam 20 mg, prepared as a liquid in a soft gelatin capsule, reduced sleep latency and prolonged total sleep time. A reduction in stage shifts to Stages I and II and a reduction in time spent in Stages 0 + I suggest more restful sleep. The sleep "architecture" (including REM/NREM cycling, total SWS and REM time) was relatively undisturbed. Temazepam would seem to be effective as a first-line hypnotic for short-term use in stressed patients.


Apr 5, 1979·The New England Journal of Medicine·F SolomonW B Mendelson
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Jul 1, 1996·Psychopharmacology·L Parrino, M G Terzano
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Sep 25, 2003·Sleep Medicine Reviews·Shawn D Youngstedt
Jan 1, 1990·Neuroscience and Biobehavioral Reviews·G VogelA Hennessey

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