Psychobiology of the placebo response

Autonomic Neuroscience : Basic & Clinical
Sibylle Klosterhalfen, Paul Enck

Abstract

The nature and determinants of the placebo response are widely unknown and are discussed controversially. This review presents a unifying concept for the understanding of the placebo response in clinical trials and practice based on three components: "Regression to the mean", "Pavlovian conditioning", and "Signal detection theory", and discusses the respective literature in light of experimental and clinical findings from psychology, psychiatry, neurology, and gastroenterology, with specific emphasis on "brain imaging" of the placebo response.

References

Oct 1, 1989·The American Journal of Psychiatry·P E KeckS L McElroy
Aug 24, 1999·Gut·S J Veldhuyzen van ZantenA R Zinsmeister
Oct 6, 2000·Psychosomatic Medicine·S KlosterhalfenP Enck
Aug 11, 2001·Science·R de la Fuente-FernándezA J Stoessl
Jan 5, 2002·The American Journal of Psychiatry·Andrew F LeuchterMichelle Abrams
Feb 9, 2002·Science·Predrag PetrovicMartin Ingvar
May 3, 2002·The American Journal of Psychiatry·Helen S MaybergPaul A Jerabek
Nov 14, 2002·Behavioural Brain Research·Raúl de la Fuente-FernándezA Jon Stoessl
Nov 27, 2002·Evaluation & the Health Professions·Lorraine G Allan, Shepard Siegel
Feb 4, 2003·Nature Reviews. Neuroscience·Jacqueline N Wood, Jordan Grafman
Feb 21, 2004·Science·Tor D WagerJonathan D Cohen
Apr 28, 2004·NeuroImage·Matthew D LiebermanEmeran A Mayer
May 18, 2004·Nature Neuroscience·Fabrizio BenedettiLeonardo Lopiano
Mar 24, 2005·Psychosomatic Medicine·Sibylle KlosterhalfenPaul Enck
May 27, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P Enck, S Klosterhalfen

❮ Previous
Next ❯

Citations

Aug 8, 2009·Psychosomatic Medicine·John M KelleyTed J Kaptchuk
Jan 31, 2012·Trends in Pharmacological Sciences·Bettina K Doering, Winfried Rief
Feb 9, 2011·The International Journal of Neuropsychopharmacology·Ayşegül YildizRoss J Baldessarini
Oct 16, 2015·European Journal of Gastroenterology & Hepatology·Annemieke Y ThijssenAd A M Masclee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Related Papers

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Fabrizio BenedettiJon-Kar Zubieta
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Fabrizio BenedettiAntonella Pollo
© 2021 Meta ULC. All rights reserved