Psychological and behavioral effects of genetic risk testing for obesity: a systematic review

Personalized Medicine
Emily K CheeraMee Young Hong

Abstract

Interest is growing in the use of genetic risk testing for lifestyle-related chronic diseases, including obesity, to promote health behavior change. A systematic review of the literature was conducted to determine the effects that genetic risk feedback for obesity may have on psychological and behavioral factors influencing weight. The MEDLINE/PubMed online database was searched using predefined search terms. The studies revealed that risk feedback may increase motivation to improve health behaviors, especially among individuals at higher genetic risk. Overweight and obese individuals seemed to experience additional psychological benefits when provided an external explanation for their weight status. While the psychological benefits are promising, the clinical utility of genetic risk testing for obesity remains uncertain.

References

Dec 12, 1997·Journal of Psychosomatic Research·P M Salkovskis, K A Rimes
Aug 22, 2000·Journal of Medical Ethics·R Hoedemaekers
Nov 22, 2001·Journal of the American Dietetic Association·J Harvey-BerinoE T Poehlman
Jun 9, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Dominick L FroschCaryn Lerman
Sep 20, 2007·Journal of General Internal Medicine·Winfried RiefJohannes Hebebrand
Dec 17, 2008·Nature Genetics·Cristen J WillerUNKNOWN Genetic Investigation of ANthropometric Traits Consortium
Jul 29, 2009·Health Affairs·Eric A FinkelsteinWilliam Dietz
Mar 5, 2010·The International Journal of Behavioral Nutrition and Physical Activity·Catharine Wang, Elliot J Coups
Oct 6, 2010·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Ruth E CollinsTheresa M Marteau
Oct 12, 2010·Nature Genetics·Elizabeth K SpeliotesRuth J F Loos
Apr 14, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·Ruth J F Loos
Oct 26, 2012·The Proceedings of the Nutrition Society·Jacqueline A Vernarelli
Jul 9, 2013·Journal of Genetic Counseling·S F Meisel, J Wardle
Nov 13, 2013·Clinical Trials : Journal of the Society for Clinical Trials·Catharine WangDeborah J Bowen
Jul 6, 2014·Appetite·Ilan Dar-NimrodSteven J Heine
Apr 22, 2015·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Susan Persky, Richard L Street
Aug 1, 2013·Personalized Medicine·Allison A VorderstrasseGeoffrey S Ginsburg

❮ Previous
Next ❯

Citations

Jan 1, 2017·Personalized Medicine·Adam Price-Evans
Feb 1, 2018·Translational Behavioral Medicine·Colleen M McBride
Nov 17, 2020·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Susan PerskyBrittany M Hollister

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT01355224

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
J CollinsH Truby
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
Hirohito Tsubouchi
Population Health Management
Carter CoberleyJames E Pope
© 2022 Meta ULC. All rights reserved