PMID: 8971880Dec 1, 1996Paper

Psychological and clinical effects of renal biopsy performed using sedation

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
K D BlakeL Rees

Abstract

A sedation regimen using sequential oral trinepazine, intravenous Pethco (pethidine, chlorpromazine and promethazine) and diazemuls was evaluated in children having native kidney (n = 17) and transplant kidney (n = 17) biopsies. Biopsy was successful in all cases, with no serious side effects. A self-reported scale of memory recall and pain perception showed the optimal time for biopsy to be between 30 and 90 min after the intravenous Pethco. The child's level of distress was measured by a self-reported scale, a parent-reported scale and an observational scale for doctors and nurses; 45% of children rated themselves highly distressed prior to the procedure, their parents being the best assessors of this distress. Younger children and those undergoing native kidney biopsy had less understanding of the procedure. Children's worries could be clearly categorised into procedural and outcome issues: those undergoing transplant biopsy were more worried about outcome, whereas those undergoing native kidney biopsy were more worried about the procedure.

Citations

Jan 18, 2013·Indian Journal of Pediatrics·Chen Jie, Lu Kai-Zhi
Sep 4, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Eve Mary Dorothy SmithMichael William Beresford
Aug 14, 2013·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Jennifer H StaabLi Lin

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