Psychological aspects and depression in patients with retinitis pigmentosa

European Journal of Ophthalmology
Marilita MoschosIrini Chatziralli

Abstract

To assess the psychological impact and the potential relationship between depression and visual impairment in patients with retinitis pigmentosa (RP). Our study included 34 patients with RP and 35 age- and sex-matched controls. All participants underwent a thorough ophthalmic examination including best-corrected visual acuity (BCVA), slit-lamp biomicroscopy, and dilated funduscopy, and they completed the Zung Depression Inventory questionnaire and the Patient Health Questionnaire-9 (PHQ-9). Questionnaires were rated according to specific guidelines. Statistical analysis was performed using SPSS 20.0 software. There was a statistically significant difference in PHQ-9 score and Zung score between patients with RP and controls. The BCVA differed significantly between the 2 groups as well. Older subjects presented significantly higher Zung score and PHQ-9 score, as well as worse BCVA in both eyes. Sex did not show any significant correlation as far as Zung score, PHQ-9 score, or BCVA. Zung score was correlated positively with PHQ-9 score, while both Zung and PHQ-9 score were positively correlated with BCVA. Patients with RP seem to present mild to moderate depressive symptoms in comparison with healthy control subjects without visu...Continue Reading

References

Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Jan 1, 1965·Archives of General Psychiatry·W W ZUNG
Dec 27, 2005·General Hospital Psychiatry·Alexandra MartinElmar Braehler
Nov 23, 2006·Lancet·Dyonne T HartongThaddeus P Dryja
Feb 3, 2007·Ophthalmology·Jennifer R EvansRichard P L Wormald
Mar 29, 2007·Investigative Ophthalmology & Visual Science·Albert AugustinGilles Berdeaux
Aug 8, 2007·Archives of General Psychiatry·Barry W RovnerWilliam S Tasman
Nov 29, 2007·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Karen J HaymanA John Campbell
Mar 22, 2008·The British Journal of Ophthalmology·B-J HahmH G Yu
Jan 22, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Ecosse L LamoureuxGwen Rees
Oct 2, 2009·Korean Journal of Ophthalmology : KJO·Je Hyun SeoByung Joo Lee
Apr 15, 2010·Clinical Ophthalmology·Marie S I Burstedt, Eva Mönestam
Oct 12, 2010·Psychiatry Investigation·Eun Jeong LeeYanghyun Lee
Mar 9, 2013·JAMA Ophthalmology·Alan R Morse
Jan 25, 2014·Journal of Rehabilitation Research and Development·Helena Chacón-LópezBegoña Pino
Apr 1, 2014·Research in Developmental Disabilities·Konstantinos PapadopoulosArgyro Solomou

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Citations

Mar 7, 2020·Ophthalmic Genetics·Mario ZanolliHernán Iturriaga
Nov 7, 2015·European Journal of Ophthalmology·Marilita M MoschosAnastasios Lavaris
Jul 14, 2018·Journal of Ophthalmology·Marilita M MoschosIrini Chatziralli
Dec 15, 2020·American Journal of Ophthalmology·Gabrielle D LacyK Thiran Jayasundera
Nov 16, 2020·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Manav NayeniMonali S Malvankar-Mehta

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