Psychological assessment of mothers and their daughters at the time of diagnosis of precocious puberty

International Journal of Pediatric Endocrinology
Melissa J SchoelwerErica A Eugster

Abstract

Concerns about psychological distress are often used to justify treatment of girls with precocious puberty, but there is little evidence to support these concerns. The extent to which psychological problems are associated with central precocious puberty (CPP) compared with other forms of early puberty in girls has likewise not been established. Girls presenting with untreated CPP, premature adrenarche (PA) or early normal puberty (ENP) were recruited from our pediatric endocrine clinic along with their mothers. Child psychological adjustment was assessed by child self-report and parent report. Parent self-reported personality, anxiety, and depression were also assessed. Differences between groups were explored using one-way ANOVA and Dunnett's T3 test. Sixty-two subjects (aged 7.5 ± 1.4 years, range 4.8-10.5) were enrolled, of whom 19 had CPP, 22 had PA, and 21 had ENP. Girls with ENP were significantly older (8.9 ± .9 years) than girls with CPP (6.9 ± 1.1 years, p < .001) and PA (6.6 ± 1.0 years, p < .001). Girls with PA had significantly higher BMI z-scores (1.7 ± .8) than girls with CPP (1.1 ± .6, p = .01) and ENP (1.2 ± .6, p = .04). More girls with PA and ENP were from racial minorities (47% and 50% respectively) than girl...Continue Reading

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Citations

Apr 26, 2015·Paediatric Drugs·Melinda Chen, Erica A Eugster
Jun 16, 2015·The Journal of Pediatrics·Erica A Eugster
Apr 13, 2018·Journal of Pediatric Endocrinology & Metabolism : JPEM·Valerie S L WilliamsKaren O Klein
Nov 30, 2019·Current Medical Research and Opinion·Karen O KleinPaul Nisbet
Apr 14, 2017·LGBT Health·Leena NahataAmy C Tishelman
May 2, 2019·Journal of the Endocrine Society·Erica A Eugster
Mar 3, 2021·Asian Journal of Psychiatry·Rahime Duygu TemelturkBirim Gunay Kilic
Jul 28, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·Sevinc Odabasi GunesSafak Eray
Mar 5, 2018·Hormone Research in Pædiatrics·Jani LiimattaJarmo Jääskeläinen
Jul 19, 2019·Hormone Research in Pædiatrics·Kanthi Bangalore KrishnaP G Medina Bravo

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