Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse

Cephalalgia : an International Journal of Headache
S BottiroliCristina Tassorelli

Abstract

The aim of this study was to evaluate the psychological factors associated with a negative outcome following detoxification in a 2-month follow-up in medication-overuse headache. All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion. Psychiatric conditions and personality characteristics were assessed using the Structured Clinical Interview for DSM-IV Disorders (SCID-I) and the Minnesota Multiphasic Personality Inventory (MMPI)-2. χ(2) tests, one-way analyses of variance, and odds ratios (ORs) were used. A total of 248 patients completed the follow-up: 156 stopped overuse and their headaches reverted to an episodic pattern (Group A); 23 kept overusing without any benefit on headache frequency (Group B); and 51 stopped overuse without any benefit on headache frequency (Group C). The prognostic factors for the outcome of Group B were higher scores on the correction (OR 1.128; p = 0.036), depression (OR 1.071; p = 0.05), hysteria (OR 1.106; p = 0.023), and overcontrolled hostility (OR 1.182; p = 0.04) MMPI-2 scales, whereas those for Group C were psychiatric comorbidities (OR 1.502; p = 0.021) and higher scores on the hysteria scale (OR 1.125; p = 0.004). The outcome of...Continue Reading

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Citations

Apr 13, 2017·Cephalalgia : an International Journal of Headache·Sara BottiroliUNKNOWN Comoestas Consortium
Feb 3, 2019·Acta Neurologica Scandinavica·Signe B MunksgaardTroels Wienecke
Apr 2, 2020·Headache·Nicolas VandenbusscheZaza Katsarava
Jun 6, 2018·Frontiers in Psychology·Sara BottiroliCristina Tassorelli
May 26, 2017·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·E S KristoffersenC Lundqvist
Feb 26, 2021·The Journal of Neuropsychiatry and Clinical Neurosciences·Marina LjubisavljevicSrdjan Ljubisavljevic
May 27, 2021·Acta Neurologica Scandinavica·Domenico D'AmicoAlberto Raggi
Sep 21, 2021·Cephalalgia : an International Journal of Headache·Sara BottiroliCristina Tassorelli

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