Psychometric Properties of a Decisional Capacity Screening Tool for Individuals Contemplating Participation in Alzheimer's Disease Research

Journal of Alzheimer's Disease : JAD
Jennifer Burgher SeamanJennifer H Lingler

Abstract

With the growing population of individuals affected by Alzheimer's disease (AD) and related disorders, there is a pressing demand for research on late-life cognitive disorders. However, this population's high risk for decisional incapacity necessitates evaluation of capacity to consent to research participation, adding cost and complexity to the research process. The University of California, San Diego Brief Assessment of Capacity to Consent (UBACC) was initially validated in a sample of persons with schizophrenia and healthy controls. To assess the psychometric properties of the UBACC when used in a sample of individuals contemplating participation in AD research. The UBACC was administered to a convenience sample (n = 132) consisting of individuals with mild to moderate cognitive impairment (n = 52), their study partners (n = 52), and healthy older adults control subjects (n = 30), as part of a broader study to evaluate perceived burden of research participation. Reliability tests, correlational analyses, and exploratory factor analytic methods were used to examine the psychometric properties of the instrument. UBACC scores were significantly associated with both global cognition (rs= 0.564, p <  0.001) and verbal fluency (rs...Continue Reading

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Citations

Mar 12, 2015·Journal of Alzheimer's Disease : JAD·Allyson Rosen, Julie C Weitlauf
Jan 5, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Valentina MoroGiuseppe Gambina
Oct 9, 2018·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Adrian ThorogoodUNKNOWN Global Alliance for Genomics and Health, Ageing and Dementia Task Team
Aug 11, 2018·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Jennifer H LinglerOscar L Lopez
Nov 4, 2016·Journal of Clinical Microbiology·Trisha N PeelRobin Patel
Dec 24, 2019·Journal of Alzheimer's Disease : JAD·Rachel K B HamiltonCarey E Gleason

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Software Mentioned

SPSS
MacCAT
PASW
CR

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