Psychopharmacologic treatment of depression in the medically ill

Psychosomatics
K Beliles, A Stoudemire

Abstract

Appropriate selection of an antidepressant agent in medically ill patients requires a careful risk-benefit assessment matching the pharmacokinetic and pharmacodynamic properties of the drug being considered against the patient's physiological vulnerabilities, potential for drug interactions, and primary symptoms of the patient's depression. While in the past antidepressant drug selection was limited by the almost sole availability of the tricyclic antidepressants, newer drugs such as selective serotonin reuptake inhibitors, bupropion, and venlafaxine have vastly simplified treating depression in the medically ill. In refractory cases of depression in patients with medical illness, electroconvulsive therapy can be used with appropriate anesthetic management.

References

Apr 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·V Wils
Dec 1, 1991·International Clinical Psychopharmacology·S J Warrington
Jan 1, 1991·European Journal of Clinical Pharmacology·K DalhoffJ Lund
Jan 1, 1991·International Clinical Psychopharmacology·D BaldwinS Montgomery
Jan 1, 1989·Psychopharmacology·J G EdwardsS Papayanni-Papasthatis
Nov 1, 1988·General Hospital Psychiatry·A Stoudemire, P Atkinson
Jan 1, 1987·International Journal of Psychiatry in Medicine·W Katon
Feb 1, 1986·Acta Psychiatrica Scandinavica·S NielzénR Svensson
Mar 1, 1987·Digestive Diseases and Sciences·D S GreenbaumN A Halvorsen
Jan 1, 1987·European Journal of Clinical Pharmacology·S H CurryM M Wolfe
May 1, 1985·Journal of Clinical Pharmacology·E F Coccaro, L J Siever
Apr 1, 1984·The American Journal of Psychiatry·R M BerlinS W Ahmed
Mar 1, 1983·British Journal of Clinical Pharmacology·R JochemsenD D Breimer
May 26, 1993·JAMA : the Journal of the American Medical Association·A H GlassmanJ T Bigger
Oct 1, 1995·Journal of Clinical Psychopharmacology·T A KetterR M Post

❮ Previous
Next ❯

Citations

Oct 14, 2004·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Katrin ReuterMartin Härter
Jun 1, 2006·Current Psychiatry Reports·Lesley M Arnold
May 16, 2009·Advances in Therapy·Nour T BaghdadyRoger S McIntyre
Oct 4, 2002·Biological Psychiatry·K Ranga R KrishnanCynthia Wainscott
Jul 6, 2000·Journal of Psychosomatic Research·F Lespérance, N Frasure-Smith
May 6, 1999·General Hospital Psychiatry·C P Leeman
Mar 18, 2005·Seminars in Dialysis·Eliana TossaniMaurizio Fava
Feb 29, 2000·The Western Journal of Medicine·J Turner, B Kelly
Jan 11, 2005·Postgraduate Medical Journal·S U ShahS White
Jun 21, 2002·Psychosomatics·Graeme C SmithDean P McKenzie
Jun 21, 2002·Psychosomatics·Graeme C SmithThomas Trauer
Jun 10, 2006·Arthritis Research & Therapy·Lesley M Arnold
Feb 25, 2006·Primary Care Companion to the Journal of Clinical Psychiatry
Jan 15, 2015·Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses·Sarah K SpilmanPeter M Tonui
Apr 17, 2004·Clinical Pharmacokinetics·Catherine C Crone, Geoffrey M Gabriel
Jan 22, 2004·Journal of Palliative Medicine·Linda Ganzini, Steven K Dobscha
Apr 21, 2001·The New England Journal of Medicine·R Gross
Oct 17, 2007·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Lesley M Arnold
Dec 6, 2012·Pain Research and Treatment·Enrico BellatoDavide Blonna
Apr 14, 2010·The Psychiatric Clinics of North America·Lesley M Arnold
Jan 10, 2012·Pain Practice : the Official Journal of World Institute of Pain·Catherine ReedRalph Swindle
Jun 1, 2004·Expert Review of Pharmacoeconomics & Outcomes Research·J Robert Swenson
Jun 10, 2003·Clinical Journal of Oncology Nursing·Libby Bowers, Deborah A Boyle
Dec 1, 2000·Depression and Anxiety·J P Staab, D L Evans

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.