Psychopharmacotherapy of Obsessive-Compulsive Symptoms within the Framework of Tourette Syndrome

Current Neuropharmacology
Aribert Rothenberger, Veit Roessner

Abstract

While Behavioral Therapy (BT) should be recommended as the first step in the treatment of OCD as well as TS, medication can be added for augmentation and in certain situations (e.g. family preference, BT not available or feasible) the priority may even reverse. This narrative review is given on the complexity of drug treatment in patients comorbid with obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) and other tic problems. OCD with TS is a co-occurring combination of the two generally delimitable, but in detail, also overlapping disorders which wax and wane with time but have different courses as well as necessities and options of treatment. Distinct subtypes like "tic-related OCD" are questionable. Obsessive-compulsive symptoms (OCS) and tics are frequently associated (OCS in TS up to 90%, tics in OCD up to 37%). Sensory-motor phenomena like urges and just-right feelings reflect some behavioral overlap. The main additional psychopathologies are attention-deficit hyperactivity disorder (ADHD), mood problems and anxiety. Also, hair pulling disorder and skin picking disorder are related to OCD with TS. Hence, the assessment and drug treatment of its many psychopathological problems need high clinical experience, ca...Continue Reading

Associated Clinical Trials

Mar 12, 2021·Joseph Jankovic, Joseph Jankovic

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Citations

Mar 20, 2020·Journal of Child and Adolescent Psychopharmacology·Liping YuYing Li
Dec 4, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·Yu P Sivolap
Feb 23, 2021·Expert Review of Neurotherapeutics·Joanna H Cox, Andrea E Cavanna
May 8, 2021·Neuropsychiatric Disease and Treatment·Natalia Szejko, Kirsten R Müller-Vahl
Jul 27, 2021·Movement Disorders Clinical Practice·Andrew Billnitzer, Joseph Jankovic
Nov 11, 2021·European Child & Adolescent Psychiatry·Veit RoessnerKerstin J Plessen

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psychopharmacotherapy

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