PMID: 15231554Jul 3, 2004Paper

Psychotherapy alone and combined with pharmacotherapy in the treatment of depression

The British Journal of Psychiatry : the Journal of Mental Science
Frans de JongheJack Dekker

Abstract

The relative efficacy of psychotherapy and combined therapy in the treatment of depression is still a matter of debate. To investigate whether combined therapy has advantages over psychotherapy alone. A 6-month randomised clinical trial compared Short Psychodynamic Supportive Psychotherapy (n=106) with combined therapy (n=85) in ambulatory patients with mild or moderate major depressive disorder diagnosed using DSM-IV criteria. Antidepressants were prescribed according to a protocol providing four successive steps in case of intolerance or inefficacy: venlafaxine, selective serotonin reuptake inhibitor, nortriptyline and nortriptyline plus lithium. Efficacy was assessed using the 17-item Hamilton Rating Scale for Depression, the Clinical Global Impression of Severity and of Improvement, and the depression sub-scale of the Symptom Checklist. The advantages of combining antidepressants with psychotherapy were equivocal. Neither the treating clinicians nor the independent observers were able to ascertain them, but the patients experienced them clearly. The advantages of combining antidepressants with psychotherapy are equivocal.

References

Feb 1, 1985·Archives of General Psychiatry·A T BeckD Budenz
Dec 1, 1967·The British Journal of Social and Clinical Psychology·M Hamilton
Jan 1, 1984·Archives of General Psychiatry·G E MurphyP J Lustman
Sep 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·I M BlackburnJ E Christie
Jan 1, 1994·Journal of the American Psychoanalytic Association·F De JongheR Janssen
Apr 1, 1993·Journal of Consulting and Clinical Psychology·S D HollonD D Davis
Nov 21, 1997·Archives of General Psychiatry·M E ThaseD J Kupfer
May 12, 2000·Archives of General Psychiatry·A T HarveyS H Preskorn
Apr 21, 2001·Journal of Affective Disorders·F de JongheJ Peen
Mar 28, 2003·Journal of Personality Disorders·Simone KoolBarteld Puite

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Citations

Mar 18, 2008·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·M Hautzinger
Feb 3, 2011·Journal of Immigrant and Minority Health·Jie Chen, Arturo Vargas-Bustamante
Apr 1, 2014·Journal of Affective Disorders·Pim CuijpersAnnemieke van Straten
Apr 28, 2009·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Henricus L VanRobert Schoevers
Jul 21, 2010·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Mariëlle HendriksenJack Dekker
Feb 8, 2006·The Journal of Nervous and Mental Disease·Michael Bond, J Christopher Perry
Apr 14, 2006·Current Opinion in Psychiatry·Michael Bond
Mar 1, 2012·The Journal of Nervous and Mental Disease·Jack J M Dekker, Rien Van
Jan 11, 2013·Depression Research and Treatment·Rachel E Maddux, Lars-Gunnar Lundh
Aug 19, 2007·Psychotherapy and Psychosomatics·Giuseppe MainaFilippo Bogetto
Jan 11, 2014·Annual Review of Psychology·W Edward Craighead, Boadie W Dunlop
Apr 5, 2014·The Journal of Behavioral Health Services & Research·Jie Chen, Rada Dagher
Apr 25, 2007·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Michael BauerUNKNOWN WFSBP Task Force on Unipolar Depressive Disorders
May 25, 2007·Journal of Affective Disorders·Henricus L VanJack Dekker
Dec 30, 2006·European Psychiatry : the Journal of the Association of European Psychiatrists·Saskia M de MaatFrans de Jonghe
Nov 19, 2011·Clinical Psychology & Psychotherapy·Stephan KöhlerThomas Fydrich
Jul 22, 2014·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Andre Goettems BastosClarissa Marceli Trentini
Jun 5, 2015·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Peter Fonagy
Jul 25, 2013·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Michael BauerUNKNOWN World Federation of Societies of Biological Psychiatry. Task Force on Unipolar Depressive Disorders
Aug 26, 2015·The Lancet. Psychiatry·Falk LeichsenringChristiane Steinert
Sep 10, 2014·Journal of Affective Disorders·Falk Leichsenring, Henning Schauenburg
Jan 17, 2014·Journal of Korean Medical Science·Seon-Cheol ParkYong Chon Park
Nov 6, 2013·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Mariëlle HendriksenJack Dekker
May 21, 2016·Psychodynamic Psychiatry·Jack M Gorman
Jan 6, 2017·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Sagar V ParikhArun V Ravindran
Jan 6, 2017·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Falk Leichsenring, Christiane Steinert
Aug 30, 2008·Clinical EEG and Neuroscience·Desirée SpronkPaul B Fitzgerald
Jun 9, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Mark Hyman RapaportCharles B Nemeroff
May 16, 2017·Journal of Neurology, Neurosurgery, and Psychiatry·Alejandro HorgaMary M Reilly
Mar 15, 2006·Expert Review of Neurotherapeutics·Michael E Thase
Dec 18, 2019·The Cochrane Database of Systematic Reviews·Philippa DaviesNicola Wiles

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