Psychotic mania as the solitary manifestation of neurosyphilis

Annals of General Psychiatry
Eun Hyun SeoHyung-Jun Yoon

Abstract

Neurosyphilis remains a diagnostic challenge in current psychiatric practice because of its pleomorphic psychiatric manifestations. Although neurosyphilis can present with a wide range of psychiatric symptoms, psychotic mania as its solitary manifestation is an unusual phenomenon. A 46-year-old man, with no history of any psychiatric disorder, exhibited abruptly developed symptoms of psychotic mania. He was admitted to a psychiatric ward for further evaluation and treatment. Upon admission, his cognitive function was unimpaired, and the hyperactivity was not severe. Also, no abnormalities were found upon neurological examination and brain magnetic resonance imaging. He was initially diagnosed as bipolar disorder with psychotic features. On the 3rd day after admission, he was confirmed as having neurosyphilis by analysis of cerebrospinal fluid and treated with intravenous penicillin-in combination with blonanserin-an atypical antipsychotic drug. After 2 weeks of treatment, most of the symptoms had abated. The present case emphasizes that patients presenting with atypical psychiatric manifestation should be screened for possible syphilis, particularly in the absence of previous psychiatric history, and suggests that combination o...Continue Reading

References

Jan 1, 1969·The British Journal of Psychiatry : the Journal of Mental Science·K Dewhurst
Mar 5, 2002·The Journal of Clinical Psychiatry·David J KupferDebra A Stapf
Nov 19, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·M Timmermans, J Carr
Sep 20, 2007·Psychosomatics·Francis M Sanchez, Marc H Zisselman
Aug 14, 2008·The International Journal of Neuroscience·C H MitsonisD Vassilopoulos
Jun 27, 2009·General Hospital Psychiatry·Fabian FriedrichMartin Aigner
Jul 16, 2010·CNS Neuroscience & Therapeutics·Khalil G Ghanem
Jun 15, 2013·Neuropsychiatric Disease and Treatment·Tomomi TenjinNoboru Yamaguchi
Nov 20, 2013·The Journal of Neuropsychiatry and Clinical Neurosciences·Rochelle Melina Kinson, Lai Gwen Chan

Related Concepts

Mental Disorders
Bipolar Disorder
Cerebrospinal Fluid
Cognition
Male Population Group
Neurosyphilis
Penicillin G
Antipsychotic Agents
Hospital Admission
Evaluation

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