Psychotic mania associated with mefloquine in a bipolar patient

Southern Medical Journal
Meredith BrumbaughHudson Hsieh

Abstract

A 63-year-old male patient with a history of bipolar I disorder presented to the emergency department in an acutely psychotic state. The patient had just returned from vacation in a malarial high-risk area and, as a result, had taken five weekly doses of mefloquine for prophylaxis. The patient's bipolar disorder was being treated with lithium, and he had been stable for about 8 years. All organic causes of psychosis were ruled out. The patient was admitted to the inpatient psychiatric unit and was treated with quetiapine until he was stable enough to return home.

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Citations

Jun 26, 2012·BMJ Case Reports·John LallyElizabeth Walsh
Jan 29, 2009·Travel Medicine and Infectious Disease·Stephen Toovey
Oct 18, 2016·Drug Safety - Case Reports·Jeffrey LivezeyLouis Cantilena
May 18, 2010·Journal of Clinical Psychopharmacology·Silvia YelmoRamón Gracia-Marco
Oct 4, 2013·Journal of Medicinal Chemistry·László VégnerAndrás Málnási-Csizmadia

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