Psychotropic medication use trends in a large pediatric and young adult solid organ transplant population

Pediatric Transplantation
Chase SamselPatricia Ibeziako

Abstract

This study describes psychotropic medication use in a pediatric and young adult solid organ transplant population. We conducted a retrospective review of the lifetime incidence of psychotropic medication use and associated characteristics in patients seen over a 6-year period at a large pediatric transplant center utilizing univariate and multivariate statistical analyses. The lifetime incidence of psychotropic medication use was 36.5% in 393 patients. Transplant psychiatry provided psychopharmacological consultation to 21.9% of patients. Controlling for age and sex, there were significant associations between psychotropic use and thoracic organ disease (heart/lung) (AOR = 2.14; 95% CI: 1.2-3.8; P = 0.01), White race (P = 0.0002), histories of depressive/mood disorders (AOR = 3.68; 95% CI: 1.8-7.7; P = 0.0005), attention/learning disorders (AOR = 3.30; 95% CI: 1.6-6.9; P = 0.001), acute and post-traumatic stress disorders (AOR = 10.54; 95% CI: 2.6-42.8; P = 0.001), and experiencing bullying (AOR = 2.16; 95% CI: 1.03-4.55; P = 0.04). In unadjusted tests, significant associations were found between lifetime psychotropic usage and patient anxiety history (OR = 2.26; 95% CI: 1.5-3.5; P = 0.0002), end-of-life disease progression (OR...Continue Reading

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Citations

Jul 2, 2019·Current Opinion in Pediatrics·Kathryn ChatfieldMelanie D Everitt
Sep 15, 2020·Journal of Pediatric Gastroenterology and Nutrition·Jennifer Vittorio
Nov 18, 2020·Pediatric Transplantation·Amy E Bobrowski

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