pUb6060: a broad-host-range, DNA polymerase-I-independent ColE2-like plasmid

Plasmid
M B AvisonP M Bennett

Abstract

A ColE2-like, cryptic plasmid, pUB6060, of 5.8 kb has been found in a clinical isolate of Plesiomonas shigelloides. The complete sequence of pUB6060 has been determined and reveals a number of interesting features about the plasmid. The ColE2-like replication locus is linked to a functional ColE1-like mobilization locus. Replication is, unusually for ColE2 replicons, DNA polymerase-I-independent and may involve two, rather than the usual one, plasmid-encoded functions. Additionally, it carries two ORFs encoding products of unknown function. The pUB6060 replicon maintains a moderate plasmid copy number (10 per chromosome copy) and permits replication in diverse gram-negative bacteria.

References

Mar 1, 1992·Molecular Microbiology·N Ogasawara, H Yoshikawa
Jan 1, 1991·Journal of Clinical Microbiology·S L AbbottJ M Janda
Sep 1, 1990·Molecular Microbiology·M Motallebi-VesharehC M Thomas
Jun 1, 1989·Molecular & General Genetics : MGG·A C BoydD J Sherratt
Apr 1, 1987·Infection and Immunity·D A HerringtonM M Levine
Dec 1, 1994·Journal of Bacteriology·S HiragaT Itoh
Jun 1, 1995·Antimicrobial Agents and Chemotherapy·K BushA A Medeiros
Jun 10, 1998·Microbiology and Molecular Biology Reviews : MMBR·G del SolarR Díaz-Orejas
Jun 6, 2000·The Journal of Antimicrobial Chemotherapy·M B AvisonT R Walsh
Jun 30, 2000·Plasmid·B AlbigerP Bennett
Jun 30, 2000·Plasmid·N TavakoliP Bennett
Jan 1, 1963·Annual Review of Microbiology·J MARMURM MANDEL

❮ Previous
Next ❯

Citations

Jan 28, 2011·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Cristina PellegriniMariagrazia Perilli
Jan 24, 2006·Journal of Bacteriology·Masaru YaguraTateo Itoh
Feb 23, 2010·BMC Microbiology·Wilfried RozhonBrigitte Poppenberger
Oct 17, 2009·Journal of Biomedicine & Biotechnology·Daniela LepkaGottfried Wilharm
Jul 8, 2008·Journal of Biotechnology·Andreas SchlüterAlfred Pühler
Aug 29, 2013·FEMS Microbiology Letters·Aayushi Jain, Preeti Srivastava
Dec 11, 2020·ACS Synthetic Biology·Anton KanNeel S Joshi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.