PMID: 9172272Apr 18, 1997Paper

Pubertal development and onset of psychosis in childhood onset schizophrenia

Psychiatry Research
J A FrazierJ L Rapoport

Abstract

In this study, pubertal development was examined for a sample of children and adolescents with childhood onset schizophrenia (COS) defined as psychosis by age 12. Developmental and psychiatric histories were obtained for 28 adolescents (mean age 14.5 +/- 2.3 years) with severe, treatment refractory COS (14 males, 14 females). Age of onset of psychosis was also examined in relation to menarche and development of secondary sex characteristics. Girls had a trend towards developing secondary sex characteristics earlier than boys (P = 0.06), consistent with North American norms. Males (N = 14) and females (N = 14) had similar age of onset of psychosis. The age of development of secondary sex characteristics was associated with onset of psychosis for girls, but this finding was driven by one outlier. There was no significant correlation between development of psychosis and menarche. Neither male nor female probands differed significantly from their well siblings or from North American norms in their age of onset of pubertal development. There was no evidence of early onset of secondary sex characteristics for this sample. Finally, there was an absence of a clear relationship between onset of psychosis and indices of sexual developmen...Continue Reading

References

Jan 1, 1992·Child Psychiatry and Human Development·D R RosenbergL Gourash
Sep 1, 1992·Journal of the American Academy of Child and Adolescent Psychiatry·W H GreenM Bassiri
Jan 1, 1992·Schizophrenia Bulletin·J A LiebermanA Loebel
Jan 1, 1990·Schizophrenia Bulletin·M C AngermeyerJ M Goldstein
Mar 1, 1990·The Journal of Clinical Endocrinology and Metabolism·R L Rosenfield
May 1, 1989·Journal of the American Academy of Child and Adolescent Psychiatry·A T RussellC Sammons
Sep 1, 1988·European Archives of Psychiatry and Neurological Sciences·M C Angermeyer, L Kühn
Feb 1, 1988·Psychological Medicine·F R VolkmarR Paul
Apr 1, 1971·The British Journal of Psychiatry : the Journal of Mental Science·I KolvinA McNay
Aug 1, 1967·Journal of Psychosomatic Research·R L CaseyT H Holmes
May 1, 1982·Archives of General Psychiatry·S M Monroe
Apr 1, 1980·Archives of General Psychiatry·E S Paykel
Jul 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·K McKennaJ L Rapoport
Oct 1, 1995·Journal of the American Academy of Child and Adolescent Psychiatry·J Alaghband-RadJ L Rapoport
May 1, 1995·Schizophrenia Research·K Maurer, H Häfner
Jun 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·K McKennaJ L Rapoport
Jun 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·J A FrazierJ L Rapoport
Jun 1, 1993·Schizophrenia Research·P M GaldosR M Murray
Jan 23, 1998·Psychiatry Research·L K JacobsenA J Zametkin
Jul 1, 1997·Indian Journal of Psychiatry·T N Srinivasan, S Latha

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Citations

Dec 21, 2000·Current Psychiatry Reports·J L Rapoport, G Inoff-Germain
Dec 6, 2000·Journal of Psychiatric Research·A RuizE Miranda
Mar 17, 2000·Brain Research. Brain Research Reviews·R NicolsonJ L Rapoport
May 10, 2001·Schizophrenia Research·M E ShentonR W McCarley
Nov 16, 2007·Schizophrenia Bulletin·Jean A FrazierNikos Makris
Jul 4, 2001·Journal of the American Academy of Child and Adolescent Psychiatry·UNKNOWN American Academy of Child and Adolescent Psychiatry
Oct 9, 2012·Child and Adolescent Psychiatric Clinics of North America·Ann E MaloneyJean A Frazier
Jan 20, 2010·Psychiatry Research·Simon Lowes CollinsonSiow Ann Chong
May 16, 2009·L'Encéphale·D Bailly
Dec 3, 2005·Child and Adolescent Psychiatric Clinics of North America·Lynelle E Thomas, Scott W Woods
Dec 1, 1999·Biological Psychiatry·R Nicolson, J L Rapoport
Jan 29, 2011·Early Intervention in Psychiatry·Nora S VyasBasant K Puri
Sep 30, 2014·Early Intervention in Psychiatry·Elena Rubio-AbadalSusana Ochoa
Nov 18, 2009·Issues in Mental Health Nursing·Heeyoung Lee, Karen Schepp
Aug 2, 2008·Expert Opinion on Pharmacotherapy·Vishal MadaanDaniel R Wilson
Jul 6, 2014·Scientific Reports·Zhi YangPeter A Bandettini
Jun 27, 2020·The Journal of International Medical Research·Yuanyuan HanTao Li
Jul 29, 2010·Expert Review of Neurotherapeutics·Nora S VyasBasant K Puri
Aug 3, 2007·International Review of Psychiatry·Marinos Kyriakopoulos, Sophia Frangou
Feb 15, 2008·Pediatrics·Mari S GolubJorma Toppari

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