Abstract
To examine the association between pubertal timing and cardiometabolic markers among adolescents. We used data from Dutch adolescents participating in a birth cohort study. The study population for the current study consisted of 799 adolescents of whom data were available for at least 1 of the exposure variables (pubertal timing and/or age at menarche) and any of the cardiometabolic markers (waist circumference, cholesterol, blood pressure [BP], glycated hemoglobin) measured at age 16 years. Adolescents self-reported pubertal development at ages 11, 14, and 16 years. We categorized participants with early (84 girls, 88 boys), intermediate (240 girls, 211 boys), or late pubertal timing (89 girls, 85 boys). We estimated differences in cardiometabolic markers using linear regression analysis. Girls with early pubertal timing had 1.54 cm larger waist circumference (95% CI .05; 3.03) and 3.98 mm Hg higher systolic BP (95% CI 1.69; 6.27) at age 16 years than girls with intermediate pubertal timing. The association with systolic BP remained after adjusting for childhood body mass index (BMI) (age 8 years) but attenuated after adjusting for BMI in adolescence (age 16 years). Boys with early pubertal timing had 0.79 mmol/mol lower glyca...Continue Reading
References
Feb 8, 1986·Lancet·J M Bland, D G Altman
Oct 8, 1999·Diabetes·A MoranA R Sinaiko
Mar 10, 2000·Pediatric Research·A M FredriksJ M Wit
Nov 25, 2000·American Journal of Epidemiology·G A Colditz, B Rosner
Oct 24, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M G FrontiniG S Berenson
Dec 22, 2004·Hypertension·Thomas G PickeringUNKNOWN Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research
Feb 25, 2005·The Journal of Clinical Endocrinology and Metabolism·Karen E RemsbergRoger M Siervogel
Feb 2, 2006·Human Reproduction Update·UNKNOWN ESHRE Capri Workshop Group
Apr 3, 2007·Lancet·George C Patton, Russell Viner
Feb 15, 2008·Pediatrics·Paul B Kaplowitz
Oct 24, 2008·American Journal of Human Biology : the Official Journal of the Human Biology Council·Xiaoli Chen, Youfa Wang
Feb 4, 2009·International Journal of Epidemiology·B K JacobsenG E Fraser
May 27, 2009·Child Development·Elizabeth A ShirtcliffSeth D Pollak
Jun 23, 2009·Trends in Endocrinology and Metabolism : TEM·M Lynn AhmedDavid B Dunger
Nov 3, 2009·The Journal of Clinical Endocrinology and Metabolism·Rajalakshmi LakshmanKen K Ong
Oct 6, 2010·Reproductive Biology and Endocrinology : RB&E·Olga Karapanou, Anastasios Papadimitriou
Oct 19, 2011·European Journal of Epidemiology·Koji TamakoshiUNKNOWN JACC Study Group
May 26, 2012·Public Health Nutrition·Lisanne M VerweijWillem van Mechelen
Jun 21, 2012·Pediatric Obesity·T J Cole, T Lobstein
Nov 21, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·P Prentice, R M Viner
Jan 15, 2013·International Journal of Epidemiology·Alet H WijgaHenriëtte A Smit
Apr 13, 2013·PloS One·Henk TalmaRemy A Hirasing
Apr 1, 1988·Journal of Youth and Adolescence·A C PetersenA Boxer
Jun 13, 2014·American Journal of Epidemiology·Dimitrios CharalampopoulosKen K Ong
Dec 17, 2014·Circulation·Dexter CanoyBenjamin J Cairns
Mar 24, 2015·Social Science & Medicine·Lindsay Till Hoyt, April M Falconi
Jun 19, 2015·Scientific Reports·Felix R DayJohn R B Perry
Citations
Jan 10, 2019·International Journal of Epidemiology·Izzuddin M ArisEmily Oken
Aug 1, 2019·Scientific Reports·Rebecca HardyDiana Kuh
Apr 14, 2020·Nutrition & Metabolism·Nor Aishah EmiGeeta Appannah
Sep 27, 2020·Stress and Health : Journal of the International Society for the Investigation of Stress·Tiwaloluwa A AjibewaRebecca E Hasson
Aug 5, 2019·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Maria J FonsecaAna C Santos
Mar 26, 2021·BMC Medicine·Gillian M MaherLinda M O'Keeffe
Jul 4, 2021·The Journal of Clinical Hypertension·Yanhui LiJun Ma
Nov 11, 2021·Human Reproduction·Izzuddin M ArisJorge E Chavarro