Pubic hair of infancy: endocrinopathy or enigma?

Pediatrics
Todd D Nebesio, Erica A Eugster

Abstract

Pubic hair of infancy is a rare condition that has not been well-characterized. A retrospective chart review of infants <12 months of age who presented to our pediatric endocrine clinics with isolated pubic hair over the last 5 years was performed. Eleven patients were identified (6 male and 5 female). The average age at diagnosis was 8.3 +/- 2.0 months. The majority of patients (73%) had pubic hair in an atypical location. Growth pattern, laboratory evaluation, and bone-age radiographs were unremarkable for all the infants. Of the infants that returned for follow-up, pubic hair resolved by the age of 11.0 +/- 1.5 months. From our experience and review of the literature, we suggest that isolated pubic hair of infancy is a benign entity. However, long-term follow-up needs to be done to determine if pubic hair of infancy is an atypical variant of premature adrenarche, which may place these patients at risk for later adult disease.

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Citations

Jul 24, 2007·Journal of Pediatric Endocrinology & Metabolism : JPEM·Paul Kaplowitz, Steven J Soldin
Jul 2, 2008·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Alexander K C Leung, Wm Lane M Robson
Jan 16, 2007·Current Problems in Pediatric and Adolescent Health Care·Todd D Nebesio, Erica A Eugster
Jun 2, 2015·Journal of Pediatric Endocrinology & Metabolism : JPEM·Paul B Kaplowitz, Rinku Mehra
Apr 4, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Rafik BourayouRaja Brauner
May 31, 2011·Clinical Pediatrics·Hernâni Fernando Costa BritoSusana Paula Soares Gama de Sousa
Aug 16, 2012·Clinical Pediatrics·Julia von OettingenMadhusmita Misra
Mar 14, 2013·Clinical Pediatrics·Dominika JanusJerzy Starzyk
Sep 25, 2017·Pediatric Dermatology·Zeynep Uzan TatlıSelim Kurtoglu
Apr 1, 2021·Endocrine Reviews·Robert L Rosenfield

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