Pubic symphysis osteomyelitis in the prostate cancer survivor: clinical presentation, evaluation, and management

Urology
Shubham GuptaAndrew C Peterson

Abstract

To describe pelvic bone osteomyelitis in the prostate cancer survivor, to report on clinical presentation and treatment, and to suggest an algorithmic approach to managing this syndrome complex. A retrospective chart review from January 2011 to June 2014 was performed to identify prostate cancer patients with pubic symphysis osteomyelitis at a tertiary-care academic medical center with emphasis on genitourinary cancer survivorship. Data on clinical presentation and outcomes were reviewed. Ten patients were diagnosed with having osteomyelitis of the pubic symphysis with or without extension into the pubic rami. Three patients had associated rectal fistulas. Four patients had radical prostatectomy, 5 patients received radiotherapy, and 1 patient received high-intensity focused ultrasound as the primary treatment for prostate cancer. The most common presenting symptoms were pelvic and suprapubic pain, difficulty in walking, and recurrent urinary infections at a median of 7 years after prostate cancer treatment (range, 1.5-16 years). Eight of the 10 patients underwent pubic bone debridement with urinary and fecal diversion when needed. Two patients continue to be managed conservatively with suppressive antibiotics owing to low dise...Continue Reading

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Citations

Jan 1, 2017·Case Reports in Orthopedics·Cristiana Iacuzzo, Jacopo Monticelli
Aug 5, 2021·Journal of Bone and Joint Infection·Henry T ShuBabar Shafiq
Nov 23, 2019·Médecine et maladies infectieuses·A BeckerT Ferry
Aug 14, 2021·Journal of Surgical Case Reports·Uzoma A AneleKenneth W Angermeier

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