Dec 23, 2014

Recombination and sterility in inversion homo- and heterokaryotypes under a general counting model of chiasma interference

BioRxiv : the Preprint Server for Biology
Rajita Menon, Kirill S. Korolev


It has long been known that chiasmata are not independently generated along the chromosome, a phenomenon known as chiasma interference. In this paper, I suggest a model of chiasma interference that generalizes the Poisson model, the counting model, the Poisson-skip model and the two-pathway counting model into a single framework, and use it to derive infinite series expressions for the sterility and recombination pattern probabilities in inversion homo- and heterokaryotypes, and a closed-form expression for the special case of the two-pathway counting model in homokaryotypes.

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