Pulmonary alveolar proteinosis in a 67-year-old woman with Wegener's granulomatosis.

Journal of General Internal Medicine
Shiwan K ShahGulshan Sharma

Abstract

Mycophenolate mofetil (MM) is commonly used in patients with autoimmune diseases or who have undergone transplantation. Common side effects of MM include anemia, leukopenia, mucositis and opportunistic infections. We report an unusual case of pulmonary alveolar proteinosis (PAP) in a 67-year-old woman on MM for Wegener's granulomatosis (WG). PAP is a disease characterized by defects in macrophage-mediated processing of surfactants, leading to accumulation of periodic acid-Schiff (PAS)-positive lipoproteinaceous material within the alveolar spaces.

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Citations

Jun 12, 2013·Irish Journal of Medical Science·M J McDonnellR M Rutherford
Apr 14, 2015·Expert Review of Respiratory Medicine·Spyros A PapirisEffrosyni D Manali
Jul 15, 2015·American Journal of Clinical Dermatology·Justin P BandinoScott A Norton
May 3, 2020·The Journal of Rheumatology·Maite Silva-DíazTeresa Hermida Romero
Apr 4, 2021·International Journal of Molecular Sciences·Miriam HetzelNico Lachmann

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