PMID: 9536835Apr 16, 1998Paper

Pulmonary artery pressure: early predictor of chronic lung disease in preterm infants

Archives of Disease in Childhood. Fetal and Neonatal Edition
N V SubhedarN J Shaw

Abstract

To determine if pulmonary artery pressure (PAP) in ventilated preterm infants is independently associated with the development of chronic lung disease (CLD) and whether early assessment has any prognostic value. Two cohorts (development n = 55; and validation n = 28) of preterm infants were studied at 24 hours of age. PAP was assessed non-invasively using its inverse correlation with the corrected acceleration time to right ventricular ejection time ratio (AT:RVET(c)), calculated from the pulmonary artery Doppler waveform. Clinical and respiratory variables were also collected. Using logistic regression analysis to identify factors independently associated with CLD, a prognostic score was developed to predict CLD. The ability of the score to predict CLD was described using receiver operating characteristic (ROC) curves. Birthweight, inspired oxygen concentration, and AT:RVET(c) were independently predictive of CLD. The area under the ROC curve was 0.96 for the development and 0.89 for the validation cohort. Exclusion of AT:RVET(c) resulted in a reduction to 0.88 and 0.73, respectively. PAP is independently associated with CLD. An early assessment of PAP using AT:RVET(c) may permit the early prediction of CLD as part of a multif...Continue Reading

References

Jul 1, 1991·Archives of Disease in Childhood·R W Cooke
Jan 1, 1990·Archives of Disease in Childhood·N J Evans, L N Archer
Nov 1, 1995·The Journal of Pediatrics·M P SeppänenP O Kero
Jan 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·A B Gill, A M Weindling
May 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·A H Hamdan, N J Shaw
Jan 1, 1994·European Journal of Pediatrics·M Silverman
Jul 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·S W RyanB N Shaw
Mar 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·P Iyer, N Evans
Jan 1, 1993·Archives of Disease in Childhood·N Evans
Mar 1, 1993·Archives of Disease in Childhood·A B Gill, A M Weindling
Mar 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·P W Fowlie
Jul 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·N V Subhedar, N J Shaw
Aug 1, 1996·European Journal of Pediatrics·S W RyanB N Shaw

❮ Previous
Next ❯

Citations

Oct 22, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·M Murase, A Ishida
May 5, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·N V Subhedar, N J Shaw
Jul 18, 2002·American Journal of Respiratory and Critical Care Medicine·Robert P JankovA Keith Tanswell
Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Matthew M LaughonUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Jul 24, 2013·The Journal of Physiology·Robert GalinskyTimothy J M Moss
Sep 8, 2012·Clinics in Perinatology·Andrea Trembath, Matthew M Laughon
Jul 22, 2010·Seminars in Fetal & Neonatal Medicine·Afif F El-Khuffash, Patrick J McNamara
Sep 19, 2015·Computers in Biology and Medicine·Marcin Ochab, Wiesław Wajs
Sep 20, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Philip T LevyGautam K Singh
Oct 2, 2003·Pediatric Pulmonology·Steven L OlsenWilliam E Truog
Nov 18, 2003·Pediatric Pulmonology·Donald W ThibeaultIkechukwu I Ekekezie
Feb 22, 2005·American Journal of Physiology. Lung Cellular and Molecular Physiology·Robert P JankovA Keith Tanswell
Feb 19, 2020·Current Opinion in Pediatrics·Cecile Tissot, Yogen Singh
Sep 15, 2009·American Journal of Physiology. Lung Cellular and Molecular Physiology·Azhar MasoodA Keith Tanswell
May 26, 2017·Singapore Medical Journal·Woei Bing Poon, Keng Yean Wong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.