PMID: 9159623May 1, 1997Paper

Pulmonary autograft versus homograft replacement of the aortic valve: a prospective randomized trial

The Journal of Thoracic and Cardiovascular Surgery
F SantiniM H Yacoub

Abstract

Pulmonary autografts offer many theoretical advantages. However, the operation is complex, may interfere with right ventricular and pulmonary outflow function, and requires a longer operative time than does the homograft operation. The effects of these potential disadvantages are unknown. To clarify these issues we randomized 70 patients undergoing aortic valve replacement to an aortic homograft group (group A = 37 patients; 53%; 34 male, 3 female) or a pulmonary autograft group (group B = 33 patients; 47%; 28 male, 5 female). Ages varied from 12 to 65 years (mean 39 +/- 15 years) for group A and from 3 to 54 years (mean 29 +/- 15 years) for group B (p = not significant). Eleven patients in group A (30%) and eight in group B (24%) had previous aortic valve surgery. All patients were operated on by the same surgeon. The mean cardiopulmonary bypass time was 113 +/- 29 minutes (range 66 to 175 minutes) for group A and 151 +/- 31 minutes (range 115 to 226 minutes) for group B (p < 0.002). Mean aortic crossclamp time was 85 +/- 19 minutes (range 45 to 140 minutes) for group A and 109 +/- 20 minutes (range 74 to 164 minutes) for group B (p = 0.02). In 32 patients (86.5%) the aortic homograft was implanted as a root with coronary reim...Continue Reading

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Citations

Jul 6, 2000·The Annals of Thoracic Surgery·C J Knott-CraigM M Lane
Aug 14, 2002·The Annals of Thoracic Surgery·Jean-Michel GrindaAlain Deloche
Aug 6, 1998·The Annals of Thoracic Surgery·W F Northrup, V R Kshettry
Sep 4, 1999·The Annals of Thoracic Surgery·F M LupinettiS P Herndon
Jul 25, 2003·The Journal of Thoracic and Cardiovascular Surgery·Flavian M LupinettiGeoffrey L Rosenthal
Jan 15, 2000·International Journal of Cardiology·M A Gatzoulis
Feb 9, 2002·The Journal of Trauma·Jeff AppleGary Purdue
Feb 14, 2006·Current Opinion in Cardiology·Jian Ye, Wr Eric Jamieson
May 9, 2008·Regenerative Medicine·Francesco MignecoRavi K Birla
Jan 5, 2002·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·K SakumaK Tabayashi
Apr 17, 2007·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Hillel LaksMichael C Fishbein
Aug 4, 2001·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Thomas L. Spray
Nov 8, 2011·Journal of Vascular Surgery·Clay QuintLaura E Niklason
Sep 17, 2013·Journal of the Mechanical Behavior of Biomedical Materials·A L F SoaresF P T Baaijens
Jan 3, 2007·The Journal of Thoracic and Cardiovascular Surgery·Claudia SchmidtkeHans-H Sievers
Aug 3, 2002·Journal of Cardiothoracic and Vascular Anesthesia·Carmen B GomezRoberto R Favaloro

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