Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests

Pulmonary Medicine
Patricia Gomes Cytrangulo De MarcaAgnaldo José Lopes


Since nontuberculous mycobacterial pulmonary disease (NTM-PD) is a condition with increasing morbidity, a more detailed knowledge of radiological aspects and pulmonary function plays a relevant role in the diagnosis and appropriate therapeutic management of these patients. The purpose of this study was to evaluate changes in lung parenchyma through computed tomography (CT) densitometry and, secondarily, to analyze its correlation with pulmonary function testing (PFT) in patients with NTM-PD. This is a cross-sectional study in which 31 patients with NTM-PD and 27 controls matched by sex, age, and body mass index underwent CT pulmonary densitovolumetry and pulmonary function tests including spirometry and body plethysmograph. Based on the total lung volume (TLV) and total lung mass (TLM) measurements, the cumulative mass ratios were calculated for 3% (M3), 15% (M15), 85% (M85), and 97% (M97) of the TLV. We also calculated the complement, which is represented by TLM (100%) minus the mass of 15% (C85) or 3% (C97) of the TLV. Patients with NTM-PD presented lower values of M3 and M15 than controls, with greater significant differences in the apical third and middle third measurements. Compared to controls, patients with NTM-PD showed...Continue Reading


Jul 1, 1997·Radiographics : a Review Publication of the Radiological Society of North America, Inc·S A Rubin
Apr 10, 1999·Investigative Radiology·B C StoelJ H Reiber
Jul 21, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J A NederL E Nery
Feb 6, 2007·American Journal of Respiratory and Critical Care Medicine·David E GriffithUNKNOWN Infectious Disease Society of America
Nov 6, 2007·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Carlos Alberto de Castro PereiraSílvia Carla Rodrigues
Nov 17, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P Maureen CassidyKevin L Winthrop
Jun 12, 2010·American Journal of Respiratory and Critical Care Medicine·D Rebecca PrevotsKenneth N Olivier
Feb 14, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·C-T HuangP-C Yang
Aug 2, 2012·Respiratory Medicine·Alona MatveychukDavid Shitrit
Feb 1, 2013·QJM : Monthly Journal of the Association of Physicians·C Zheng, C H Fanta
Feb 11, 2014·Medical Physics·M StaringB C Stoel
Aug 8, 2015·The British Journal of Radiology·Gustavo B CamiloAgnaldo J Lopes
Mar 16, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jason E StoutWing Wai Yew
May 22, 2016·Respiration; International Review of Thoracic Diseases·Nasstasja WassilewChristoph Lange
Oct 26, 2016·Radiologia brasileira·Roberto MogamiAgnaldo José Lopes
Feb 22, 2017·Journal of Medical Imaging and Radiation Oncology·Gustavo Bittencourt CamiloAgnaldo José Lopes
Dec 2, 2017·American Journal of Respiratory and Critical Care Medicine·Bruce H CulverUNKNOWN ATS Committee on Proficiency Standards for Pulmonary Function Laboratories
Feb 17, 2018·BMJ Open Respiratory Research·Charles S HaworthR Andres Floto

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Sep 17, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Laura Raniere Borges Dos AnjosMarcelo Fouad Rabahi

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bronchoalveolar lavage

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