PMID: 2118446Sep 1, 1990Paper

Pulmonary diffusing capacity in left ventricular dysfunction

Chest
J L SiegelA S Teirstein

Abstract

The purpose of this study was to determine whether there are any consistent spirometric or Dsb findings in patients with LV dysfunction characterized by a clinical diagnosis of CHF and an EF less than 40 percent. We performed spirometry and Dsb in 34 patients, and found that EF correlated only with Dsb. When we separated the patients into those with rales and those without, Dsb correlated strongly with EF only in those with rales. There was no correlation with other spirometric values. Mean Dsb percent predicted was significantly lower in patients with rales despite similar mean EF. Only two of 23 patients without rales had a reduced Dsb while only one of 11 with rales had a normal Dsb. We conclude that Dsb is a good predictor of clinically evident heart failure. When rales are absent, Dsb should be normal in patients with LV dysfunction; when present, Dsb will be diminished in proportion to the EF.

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Citations

Sep 2, 1998·The American Journal of Cardiology·P AssayagF Camus
Dec 13, 1996·International Journal of Cardiology·S A EvansI D Johnston
Aug 10, 2007·International Journal of Clinical Practice·F PedersenP R Hildebrandt
Feb 1, 2013·Pulmonary Medicine·Anna ApostoloPiergiuseppe Agostoni
Aug 1, 1991·The American Review of Respiratory Disease·N A Ettinger, E P Trulock
Nov 3, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Kirk Kee, Matthew T Naughton
Aug 1, 1992·Chest·H J GroenC Hilvering
Feb 11, 2004·Chest·Brian K Gehlbach, Eugene Geppert
Mar 15, 2006·European Journal of Heart Failure·Frans H RuttenArno W Hoes
Mar 15, 1994·International Journal of Cardiology·P Faggiano
Mar 12, 1999·The American Journal of Cardiology·B MettauerJ Lonsdorfer
Jan 15, 1994·The American Journal of Cardiology·M A MungerR N Nair
Apr 7, 2010·American Heart Journal·A Selcuk AdabagRosemary F Kelly
Oct 21, 2016·International Journal of Cardiology·Rafael MesquitaMartijn A Spruit
Jun 22, 2000·Circulation·R L Johnson
Oct 13, 2018·ESC Heart Failure·Pavol SajgalikJohn A Schirger
Oct 1, 1996·Journal of Cardiovascular Pharmacology and Therapeutics·P AgostoniM D Guazzi
Feb 8, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Carmine G De PasqualeLeonard F Arnolda

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