Pulmonary embolism in patients with transvenous cardiac implantable electronic device leads

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Amit NoheriaSamuel J Asirvatham

Abstract

Cardiac implantable electronic devices (CIEDs) are commonly associated with transvenous lead-related thrombi that can cause pulmonary embolism (PE). We retrospectively evaluated all patients with transvenous CIED leads implanted at Mayo Clinic Rochester between 1 January 2000, and 25 October 2010. Pulmonary embolism outcomes during follow-up were screened using diagnosis codes and confirmed with imaging study reports. Of 5646 CIED patients (age 67.3 ± 16.3 years, 64% men, mean follow-up 4.69 years) 88 developed PE (1.6%), incidence 3.32 [95% confidence interval (CI) 2.68-4.07] per 1000 person-years [men: 3.04 (95% CI 2.29-3.96) per 1000 person-years; women: 3.81 (95% CI 2.72-5.20) per 1000 person-years]. Other than transvenous CIED lead(s), 84% had another established risk factor for PE such as deep vein thrombosis (28%), recent surgery (27%), malignancy (25%), or prior history of venous thromboembolism (15%). At the time of PE, 22% had been hospitalized for ≥ 48 h, and 59% had been hospitalized in the preceding 30 days. Pulmonary embolism occurred in 22% despite being on systemic anticoagulation therapy. Out of 88 patients with PE, 45 subsequently died, mortality rate 93 (95% CI 67-123) per 1000 person-years (hazard ratio 2.0,...Continue Reading

References

Mar 1, 1986·Pacing and Clinical Electrophysiology : PACE·W Seeger, K Scherer
Jul 1, 1996·Pacing and Clinical Electrophysiology : PACE·H G Mond, K B Stokes
Apr 20, 2001·Pacing and Clinical Electrophysiology : PACE·K WierzbowskaJ D Kasprzak
Oct 17, 2002·Pacing and Clinical Electrophysiology : PACE·Sergio Sidney do Carmo Da CostaMartino Martinelli Filho
Dec 31, 2002·The American Journal of Cardiology·Benjamin J W ChowAnthony S L Tang
Jul 25, 2003·Pacing and Clinical Electrophysiology : PACE·Frank BrackeBerry Van Gelder
Jun 24, 2004·Echocardiography·Apostolos KaravidasApostolos Zacharoulis
Oct 7, 2004·The American Journal of Medicine·Hsin-Bang LeuTsui-Lieh Hsu
Oct 30, 2004·The Annals of Thoracic Surgery·David B ColemanHenry M Spotnitz
Dec 3, 2004·Journal of Cardiovascular Electrophysiology·Cornelis J van RoodenMenno V Huisman
Nov 15, 2006·Pacing and Clinical Electrophysiology : PACE·Petri J KorkeilaKarl Eino Juhani Airaksinen
Mar 21, 2007·Journal of Thrombosis and Haemostasis : JTH·I A NaessJ Hammerstrøm
Aug 18, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Miroslav NovakJolana Lipoldova
Mar 30, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Petri KorkeilaJuhani Airaksinen
Jul 26, 2011·Revista Española De Cardiología·João Silva MarquesJoão de Sousa
Sep 3, 2013·BMJ Case Reports·Antonio D'AloiaAntonio Curnis
Apr 29, 2014·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Vaibhav R VaidyaPaul A Friedman

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Citations

Feb 24, 2016·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Charles J LenzSamuel J Asirvatham
Dec 10, 2015·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Alan SugrueSamuel J Asirvatham
Jun 4, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Susanne Bendesgaard PedersenJens Cosedis Nielsen
Dec 13, 2016·Pacing and Clinical Electrophysiology : PACE·Shiva P PonamgiSamuel J Asirvatham
Jan 8, 2019·Journal of Pharmacy Practice·Thomas M Ellington
Jan 30, 2016·Nature Reviews. Cardiology·Oussama Wazni, Bruce L Wilkoff
Apr 12, 2020·Pacing and Clinical Electrophysiology : PACE·Caio Marcos de Moraes AlbertiniRoberto Costa
Apr 26, 2019·European Heart Journal. Case Reports·Margos N PanagiotisKranidis I Athanasios
Nov 24, 2018·JACC. Clinical Electrophysiology·Amit NoheriaSamuel J Asirvatham
Jun 3, 2021·Journal of Cardiovascular Pharmacology·Murti PatelCory R Trankle
Jul 3, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Abhishek BoseSanjeev B Goyal

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