Pulmonary embolism severity before and during the COVID-19 pandemic.

The British Journal of Radiology
Vicky TilliridouMichelle Claire Williams

Abstract

Early in the coronavirus 2019 (COVID-19) pandemic, a high frequency of pulmonary embolism was identified. This audit aims to assess the frequency and severity of pulmonary embolism in 2020 compared to 2019. In this retrospective audit, we compared computed tomography pulmonary angiography (CTPA) frequency and pulmonary embolism severity in April and May 2020, compared to 2019. Pulmonary embolism severity was assessed with the Modified Miller score and the presence of right heart strain was assessed. Demographic information and 30-day mortality was identified from electronic health records. In April 2020, there was a 17% reduction in the number of CTPA performed and an increase in the proportion identifying pulmonary embolism (26%, n = 68/265 vs 15%, n = 47/320, p < 0.001), compared to April 2019. Patients with pulmonary embolism in 2020 had more comorbidities (p = 0.026), but similar age and sex compared to 2019. There was no difference in pulmonary embolism severity in 2020 compared to 2019, but there was an increased frequency of right heart strain in May 2020 (29 vs 12%, p = 0.029). Amongst 18 patients with COVID-19 and pulmonary embolism, there was a larger proportion of males and an increased 30 day mortality (28% vs 6%, p...Continue Reading

References

Sep 20, 2015·Clinical Radiology·N C D MorleyJ T Murchison
Apr 25, 2020·Circulation·Julien PoissyUNKNOWN Lille ICU Haemostasis COVID-19 Group
May 1, 2020·Thrombosis Research·Corrado LodigianiUNKNOWN Humanitas COVID-19 Task Force
May 6, 2020·Intensive Care Medicine·Julie HelmsUNKNOWN CRICS TRIGGERSEP Group (Clinical Research in Intensive Care and Sepsis Trial Group for Global Evaluation and Research in Sep
May 7, 2020·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Yong-Jian GengRichard J Castriotta
May 22, 2020·The New England Journal of Medicine·Maximilian AckermannDanny Jonigk
May 23, 2020·Nature Reviews. Immunology·Laure-Anne TeuwenPeter Carmeliet
May 31, 2020·The Lancet. Respiratory Medicine·Sharon E FoxRichard S Vander Heide
Jul 3, 2020·Journal of Thrombosis and Thrombolysis·B Mestre-GómezUNKNOWN Infanta Leonor Thrombosis Research Group
Jul 14, 2020·European Heart Journal·Charles FauvelUNKNOWN Critical Covid-19 France Investigators
Jul 24, 2020·JAMA : the Journal of the American Medical Association·Seda BilalogluJeffrey S Berger
Aug 1, 2020·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Apoorva JayarangaiahAbhishek Kumar
Aug 30, 2020·Journal of the American College of Cardiology·Girish N NadkarniValentin Fuster
Sep 11, 2020·The European Respiratory Journal·Basile MouhatNicolas Meneveau
Sep 26, 2020·Thrombosis Research·Òscar MiróUNKNOWN Spanish-French Emergency Department Investigative Team (SFEDIT)
Oct 22, 2020·The New England Journal of Medicine·Jehan F ChowdhuryJean M Connors
Oct 25, 2020·Nature Reviews. Clinical Oncology·Emma Greenwood, Charles Swanton
Nov 4, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Pietro AmeriMarco Metra
Jan 16, 2021·Journal of the American College of Cardiology·Andrew J EinsteinUNKNOWN INCAPS COVID Investigators Group
Mar 30, 2021·Radiology. Cardiothoracic Imaging·Mark KaminetzkyJane P Ko
May 27, 2021·Radiology. Cardiothoracic Imaging·Min LangBrent P Little

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes
Jennifer LombardEric Sala
Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
Brian M BoldtVincent Mysliwiec
Nederlands tijdschrift voor geneeskunde
Pieter W Kamphuisen, Rijk O B Gans
© 2021 Meta ULC. All rights reserved