Pulmonary function in obese subjects with a normal FEV1/FVC ratio

Chest
H Sahebjami, P S Gartside

Abstract

To determine pulmonary function test (PFT) profile and respiratory muscle strength (RMS) of a group of obese individuals who did not have evidence of obstructive airway disease or other underlying diseases affecting their respiratory system. Prospective, open. PFT laboratory, VA Medical Center. Sixty-three consecutive obese (body mass index greater than 27.8 kg/m2) male subjects without overt obstructive airway disease (FEV1/FVC ratio greater than 80%). Standard PFTs and maximum static inspiratory (PImax) and expiratory (PEmax) mouth pressures were determined. RMS was calculated from the following formula: (PImax+PEmax):2. Two distinct groups were identified, those with normal maximum voluntary ventilation (MVV) (> 80% predicted) and those with low MVV. Both inspiratory and expiratory flow rates (FVC, FEV1, forced expiratory flow at 50% vital capacity [V50], maximum inspiratory flow rate [MIFR]), lung volumes (vital capacity [VC], inspiratory capacity [IC], expiratory reserve volume), PImax, and RMS were significantly lower, and residual volume/total lung capacity (RV/TLC) ratio was significantly higher in obese subjects with low MVV compared with those in whom MVV was normal. MVV correlated significantly with FVC, FEV1, V50, M...Continue Reading

References

Jan 1, 1979·Respiration; International Review of Thoracic Diseases·M H LavietesL B Reichman
Jun 1, 1990·Annals of Internal Medicine·I RubinsteinV Hoffstein
Nov 1, 1986·The American Review of Respiratory Disease·T D BradleyE A Phillipson
Dec 1, 1985·Annals of Internal Medicine·T B Van Itallie
Dec 1, 1967·The American Journal of the Medical Sciences·F BarreraW L Winters
Oct 1, 1980·Chest·J M Luce

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Citations

Jun 5, 2013·Best Practice & Research. Clinical Endocrinology & Metabolism·Justin C Sebastian
Jan 16, 2004·The American Journal of Emergency Medicine·Douglas D Brunette
Mar 13, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Kenneth M SteinTimothy E Meyer
Nov 18, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Richard Sutton
May 30, 2009·Respirology : Official Journal of the Asian Pacific Society of Respirology·Tadahiko MitsumuneEiji Kajii
Jun 28, 2011·Journal of Applied Physiology·Gwen SklootAlkis Togias
Sep 13, 2008·Journal of Applied Physiology·Katina NicolacakisE R McFadden
Jun 12, 2012·Journal of Obesity·Yu-Feng Wei, Huey-Dong Wu
Dec 19, 2013·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Hasan KahramanHasan Cetin Ekerbicer
Aug 25, 2012·Lung India : Official Organ of Indian Chest Society·Swapnil J ParalikarMadhusudan B Jani
Feb 4, 2010·Obesity Surgery·Marize Jácome GonçalvesSelma Sousa Bruno
Apr 15, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S L HuangP Chou
Dec 4, 2002·Annals of Plastic Surgery·Mustafa TercanAkif Tercan
Sep 29, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·F ColletT Perez
Jul 23, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A RossiM Zamboni
Oct 21, 2011·Revista da Associação Médica Brasileira·Saulo Maia D'Ávila MeloFábio Almeida Santos
Nov 21, 1998·Chest·H Sahebjami
Sep 12, 2006·Chest·Richard L Jones, Mary-Magdalene U Nzekwu
Sep 15, 2004·Chest·Marc H LavietesRohit R Arora
Oct 1, 2011·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Beno W OppenheimerManish Parikh
Apr 1, 2011·Obesity Research & Clinical Practice·Bahar UlubasMukadder Calıkoglu
Apr 7, 2010·Annals of Emergency Medicine·James Dargin, Ron Medzon
Aug 25, 2009·Clinics in Chest Medicine·Jennifer W McCallisterJames M O'Brien
Jan 3, 2006·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·Rex A MarleyCarole Ries
Jan 15, 2002·Clinics in Chest Medicine·J Unterborn
Sep 26, 2006·The American Journal of Cardiology·Amit HabbuHisham Dokainish
Apr 24, 2001·Respiratory Medicine·W LadoskyJ P Albuquerque
Oct 22, 2015·PloS One·Alem MehariAlvin V Thomas
Aug 26, 2016·QJM : Monthly Journal of the Association of Physicians·J Thachil
Sep 30, 2010·Acta Cirúrgica Brasileira·Márcia Arruda Fajardo XavierAjith Kumar Sankarankutty
Nov 10, 2007·São Paulo Medical Journal = Revista Paulista De Medicina·Karla Luciana Magnani, Antônio José Maria Cataneo
Sep 14, 2004·Revista do Hospital das Clínicas·Joel FaintuchJoaquim José Gama-Rodrigues
Jun 15, 2017·Annals of the American Thoracic Society·John S KimDavid J Lederer
Nov 25, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·O RestaG De Pergola
Oct 31, 2009·Journal of Applied Physiology·Cheryl M SalomeNorbert Berend
Oct 31, 2009·Journal of Applied Physiology·Amanda J Piper, Ronald R Grunstein

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