Pulmonary function tests do not predict mortality in patients undergoing continuous-flow left ventricular assist device implantation

The Journal of Thoracic and Cardiovascular Surgery
Edo K S BedzraNahush A Mokadam

Abstract

To investigate the effect of pulmonary function testing on outcomes after continuous flow left ventricular assist device implantation. A total of 263 and 239 patients, respectively, had tests of forced expiratory volume in 1 second and diffusing capacity of the lungs for carbon monoxide preoperatively for left ventricular assist device implantations between July 2005 and September 2015. Kaplan-Meier analysis and multivariable Cox regressions were performed to evaluate mortality. Patients were analyzed in a single cohort and across 5 groups. Postoperative intensive care unit and hospital lengths of stay were evaluated with negative binomial regressions. There is no association of forced expiratory volume in 1 second and diffusing capacity of the lungs for carbon monoxide with survival and no difference in mortality at 1 and 3 years between the groups (log rank P = .841 and .713, respectively). Greater values in either parameter were associated with decreased hospital lengths of stay. Only diffusing capacity of the lungs for carbon monoxide was associated with increased intensive care unit length of stay in the group analysis (P = .001). Ventilator times, postoperative pneumonia, reintubation, and tracheostomy rates were similar ...Continue Reading

Citations

Oct 13, 2018·ESC Heart Failure·Pavol SajgalikJohn A Schirger
Oct 31, 2020·Journal of Cardiac Surgery·Nicholas R HessArman Kilic
Mar 29, 2020·Journal of the American College of Cardiology·Maya GuglinUNKNOWN ACC Heart Failure and Transplant Member Section and Leadership Council
Jan 21, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Masaki TsujiIssei Komuro

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