Pulmonary fungal infections

Respirology : Official Journal of the Asian Pacific Society of Respirology
Jeannina A Smith, Carol A Kauffman

Abstract

This review details some of the advances that have been made in the recent decade in the diagnosis, treatment and epidemiology of pulmonary fungal infections. These advances have occurred because of increasing knowledge regarding the fungal genome, better understanding of the structures of the fungal cell wall and cell membrane and the use of molecular epidemiological techniques. The clinical implications of these advances are more rapid diagnosis and more effective and less toxic antifungal agents. For example, the diagnosis of invasive pulmonary aspergillosis, as well as histoplasmosis and blastomycosis, has improved with the use of easily performed antigen detection systems in serum and bronchoalveolar lavage fluid. Treatment of angioinvasive moulds has improved with the introduction of the new azoles, voriconazole and posaconazole that have broad antifungal activity. Amphotericin B is less frequently used, and when used is often given as lipid formulation to decrease toxicity. The newest agents, the echinocandins, are especially safe as they interfere with the metabolism of the fungal cell wall, a structure not shared with humans cells. Epidemiological advances include the description of the emergence of Cryptococcus gattii...Continue Reading

References

Jul 31, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P G PappasW E Dismukes
Aug 25, 2001·American Journal of Respiratory and Critical Care Medicine·T P DoyleI M Robbins
Mar 13, 2002·Chest·Marek A Martynowicz, Udaya B S Prakash
Aug 9, 2002·The New England Journal of Medicine·Raoul HerbrechtUNKNOWN Invasive Fungal Infections Group of the European Organisation for Research and Treatment of Cancer and the Global Aspergillu
Oct 2, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marcio Nucci, Elias Anaissie
Feb 27, 2003·Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B·R T HaydenR V Lloyd
Jul 12, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shahid HusainNina Singh
Jan 8, 2004·Journal of Chemotherapy·W J Steinbach, J R Perfect
Apr 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Shahid HusainNina Singh
May 6, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marcio NucciElias Anaissie
Oct 9, 2004·Journal of Clinical Microbiology·Michelle DurkinPatricia Connolly
Jun 7, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Georgios ChamilosDimitrios P Kontoyiannis
Aug 5, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maureen M RodenThomas J Walsh
Aug 10, 2005·Seminars in Respiratory and Critical Care Medicine·L Joseph WheatJames Loyd
Oct 6, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John N GalgianiUNKNOWN Infectious Diseases Society of America
Nov 29, 2005·The Lancet Infectious Diseases·Harrys A TorresIssam I Raad
Apr 19, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Issam I RaadDimitrios P Kontoyiannis
Apr 19, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher D PfeifferNasia Safdar
Sep 21, 2006·Infectious Disease Clinics of North America·Gregory M Anstead, John R Graybill
Dec 5, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas J WalshJohn R Perfect
Jan 16, 2007·Clinical Microbiology Reviews·Carol A Kauffman
Sep 7, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L Joseph WheatUNKNOWN Infectious Diseases Society of America
Oct 16, 2007·Clinical Microbiology Reviews·Marcio Nucci, Elias Anaissie
Jan 8, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas J WalshUNKNOWN Infectious Diseases Society of America
Jan 24, 2008·Antimicrobial Agents and Chemotherapy·Peter TrokeUNKNOWN Global Scedosporium Study Group
Apr 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marisa H MiceliElias Anaissie
May 2, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J W BaddleyP G Pappas
May 9, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ben De PauwUNKNOWN National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group
May 9, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stanley W ChapmanUNKNOWN Infectious Diseases Society of America
Jul 10, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Georgios ChamilosDimitrios P Kontoyiannis
Jul 25, 2008·Medical Mycology·Fèlix GilgadoJosep Guarro
Aug 8, 2008·Journal of Clinical Microbiology·Maria V CastelliManuel Cuenca-Estrella
Sep 11, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michelle DurkinL Joseph Wheat
Oct 9, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nina SinghOlivier Lortholary
Nov 26, 2008·Medical Mycology·Juan Luis Rodriguez-TudelaManuel Cuenca-Estrella
Jan 14, 2009·Antimicrobial Agents and Chemotherapy·Alison FreifeldL Joseph Wheat
Jan 31, 2009·The Lancet Infectious Diseases·Carlo MengoliJ Peter Donnelly
Apr 21, 2009·Clinics in Chest Medicine·L Joseph Wheat

❮ Previous
Next ❯

Citations

Oct 19, 2013·Journal de mycologie médicale·H Kubisiak-RzepczykZ Adamski
Oct 10, 2012·Respirology : Official Journal of the Asian Pacific Society of Respirology·David C L Lam, John E Heffner
Sep 26, 2013·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Benjamin N NevittKathleen M Colegrove
Nov 21, 2013·Revista iberoamericana de micología·Janaina De Cássia Orlandi SardiMaria José Soares Mendes-Giannini
Mar 15, 2014·Current Opinion in Pulmonary Medicine·Alyssa R LetourneauLindsey R Baden
Dec 2, 2015·Journal of the Pediatric Infectious Diseases Society·Colleen B NashKenneth A Alexander
Oct 31, 2012·Respiratory Care·Juan F FernandezMarcos I Restrepo
Oct 27, 2012·Wiener klinische Wochenschrift·Peter PongratzChristoph Wenisch
Dec 3, 2014·Advanced Drug Delivery Reviews·Qi Tony ZhouHak-Kim Chan
Sep 14, 2014·Laboratory Medicine·Farnoush Taghizadeh, Raghuraj S Raghuwanshi M
Sep 15, 2015·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Vanessa RiveraTonny Naranjo
Mar 26, 2016·Frontiers in Microbiology·Tatiane BenaducciMaria J S Mendes-Giannini
May 20, 2015·Archivos de bronconeumología·Jose CurbeloJavier Aspa
Jan 16, 2013·Respirology : Official Journal of the Asian Pacific Society of Respirology·José M PorcelPyng Lee
Feb 18, 2015·Transplant Infectious Disease : an Official Journal of the Transplantation Society·F CicoraJ Roberti
Sep 24, 2015·Respirology Case Reports·Shotaro OkachiYoshinori Hasegawa
May 20, 2015·Emerging Infectious Diseases·Randall J NettBenjamin J Park
Sep 18, 2013·The American Journal of Tropical Medicine and Hygiene·Karen Arango-BustamanteAngel González
Dec 29, 2012·American Journal of Clinical Pathology·Akeesha A Shah, Kevin C Hazen
Oct 20, 2018·Biomédica : revista del Instituto Nacional de Salud·Nhora SilvaJuan Guillermo Restrepo
Jan 9, 2020·Future Microbiology·Nathália Lso MalaccoFrederico M Soriani
Jun 17, 2020·Journal of Investigative Medicine High Impact Case Reports·Shaher SamrahMahmoud Ayesh
Jul 15, 2020·Expert Review of Respiratory Medicine·Amit ChopraMarc A Judson
Apr 6, 2019·Frontiers in Microbiology·Danielle Silva AraújoCélia Maria de Almeida Soares
Jan 19, 2018·PLoS Neglected Tropical Diseases·Rita O OladeleDavid W Denning
Apr 1, 2014·Hepatology International·Makoto AraiOsamu Yokosuka
Aug 29, 2013·Mycopathologia·Gérald LarcherJean-Philippe Bouchara

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.