Pulmonary hypertension-"state of the art" management in 2012.

Indian Heart Journal
Anita Saxena

Abstract

Pulmonary artery hypertension (PAH) is a pathological condition of small pulmonary arteries, characterised by vascular proliferation and remodelling. The pulmonary artery pressure and pulmonary vascular resistance progressively rise, leading to right heart failure and death. Pulmonary artery hypertension may be secondary to various conditions, or it may be idiopathic where no underlying cause is identifiable. Earlier, only symptomatic treatment was available for such patients which did not change the natural history of the disease. However, over the years, improvement in understanding the pathogenesis has resulted in the development of targeted approaches to the treatment of PAH. Survival advantage has also been shown with some of the pharmacologic agents. This review article discusses the current management strategy for PAH with special emphasis on an idiopathic variety, in an Indian context.

References

Nov 1, 1990·Chest·S M LevineS G Jenkinson
May 1, 1986·British Heart Journal·A RozkovecC M Oakley
May 15, 1983·The American Journal of Cardiology·S Rich, W Lam
Jul 1, 1995·American Journal of Respiratory and Critical Care Medicine·J E LoydJ H Newman
Sep 1, 1995·The American Journal of Medicine·P HervéL Drouet
Jun 17, 1993·The New England Journal of Medicine·A GiaidD J Stewart
Jan 9, 1997·The New England Journal of Medicine·L J Rubin
Aug 1, 1997·Journal of the American College of Cardiology·S M ShapiroB H Brundage
Jun 17, 1998·Journal of the American College of Cardiology·B M WeissO M Hess
Feb 19, 1999·Lancet·A Benigni, G Remuzzi
Mar 9, 1999·Circulation·R J BarstA P Fishman
Aug 15, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·J D HosenpudR J Novick
Oct 10, 2001·Clinics in Chest Medicine·M HumbertG Simonneau
Oct 10, 2001·Clinics in Chest Medicine·J SandovalT Pulido
Oct 10, 2001·Clinics in Chest Medicine·E P Trulock
Apr 3, 2003·Critical Care Nursing Quarterly·Diane Schleyer Berkowitz, Nancy Grimes Coyne
May 10, 2003·Lancet·James R Runo, James E Loyd
Jun 13, 2003·European Heart Journal·UNKNOWN Task Force on the Management of Cardiovascular Diseases During Pregnancy of the European Society of Cardiology
Jun 25, 2003·Journal of the American College of Cardiology·Robyn J BarstUNKNOWN Beraprost Study Group
Jul 19, 2003·European Heart Journal·John DeanfieldUNKNOWN ESC Committee for Practice Guidelines
Sep 11, 2004·The European Respiratory Journal·M HumbertG Simonneau
Nov 3, 2004·Annals of Internal Medicine·Emiliano Antonio PalmieriDanilo Lembo
Feb 3, 2005·The European Respiratory Journal·V V McLaughlinL J Rubin
Mar 8, 2005·American Journal of Respiratory and Critical Care Medicine·Martin R WilkinsJ Simon R Gibbs
Sep 30, 2005·The New England Journal of Medicine·Hossein A GhofraniFriedrich Grimminger
Oct 4, 2005·The Journal of Clinical Investigation·Ralph Theo SchermulyFriedrich Grimminger
Nov 3, 2005·The European Respiratory Journal·M M HoeperJ Niedermeyer
Nov 18, 2005·The New England Journal of Medicine·Nazzareno GalièUNKNOWN Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group
Aug 22, 2006·European Journal of Clinical Investigation·V V McLaughlin
Aug 23, 2006·American Heart Journal·Alexander M WalkerGinger Constantine

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Citations

Sep 11, 2012·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Sonata JodeleRanjit Chima

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