Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review

Microbes and Infection
M F PoloP Pirina

Abstract

A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever.

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Citations

Jan 5, 2019·The British Journal of Radiology·Felipe Mussi von RankeEdson Marchiori
Jun 4, 2020·International Journal of Surgical Pathology·Dhirendra GovenderDharshnee Chetty
Nov 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Immacolata FaraoneLuigi Milella

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