Pulmonary Involvement in Sjögren Syndrome

Clinics in Chest Medicine
Jake G NataliniMaryl Kreider

Abstract

Sjögren syndrome (SS) is a progressive autoimmune disease characterized by dryness, predominantly of the eyes and mouth, caused by chronic lymphocytic infiltration of the lacrimal and salivary glands. Extraglandular inflammation can lead to systemic manifestations, many of which involve the lungs. Studies in which lung involvement is defined as requiring the presence of respiratory symptoms and either radiograph or pulmonary function test abnormalities quote prevalence estimates of 9% to 22%. The most common lung diseases that occur in relation to SS are airways disease and interstitial lung disease. Evidence-based guidelines to inform treatment recommendations for lung involvement are largely lacking.

Citations

Aug 21, 2020·European Respiratory Review : an Official Journal of the European Respiratory Society·Fabrizio LuppiAndreina Manfredi
Oct 11, 2020·BMC Pulmonary Medicine·Shunsuke UnoUNKNOWN Nontuberculous Mycobacteriosis and Bronchiectasis-Japan Research Consortium (NTM-JRC)
Feb 23, 2020·The American Journal of Medicine·Luis Alonso GonzálezPhilip Johnson
Aug 17, 2021·Medicina clínica·Jaume Mestre-Torres, Roser Solans-Laque

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