PMID: 7581937Jun 1, 1995Paper

Pulmonary oncocytoma: report of a case in conjunction with an immunohistochemical and ultrastructural study

Pathology International
Y TashiroH Manabe

Abstract

An intra-pulmonary mass in a 51 year old Japanese woman was incidentally discovered in the right middle lobe. The resected tumor was grossly well-demarcated, solid, light yellowish white in color and measured 3.0 x 2.0 x 1.5 cm in size. It was composed of a diffuse proliferation of large polygonal cells with an abundant, granular cytoplasm, and round to irregular nuclei with prominent nucleoli. Smaller eosinophilic cells with hyperchromatic nuclei and larger vacuolated cells were also observed. However, no mucin production was detected. There were neither argyrophilic nor argentaffin cells, and no serotonin-positive cells. They showed an immunoreactivity to cytokeratin and vimentin but not to alpha-actin. On electron microscopy, abundant microvilli, which have never been previously described in pulmonary oncocytomas, were observed. Occasional desmosomes and myelin figures as well as numerous mitochondria were also seen. No neurosecretory granules were present. These findings suggested that this tumor might have an epithelial origin from the bronchial serous gland with subsequent cellular degeneration.

References

Sep 1, 1977·Cancer·A Santos-BrizA Valle
Jul 27, 1979·Virchows Archiv. A, Pathological Anatomy and Histology·H Spencer
Jul 1, 1985·Journal of Surgical Oncology·H Tesluk, A Dajee
Jun 1, 1973·Cancer·R E Fechner, B R Bentinck
Jan 1, 1970·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·M Radnót, K Lapis
Jun 1, 1969·Cancer·W C Black
Apr 1, 1980·Ultrastructural Pathology·S M SajjadJ M Lukeman
Nov 1, 1982·Cancer·M J Merino, V A Livolsi
Jan 1, 1981·Virchows Archiv. A, Pathological Anatomy and Histology·A WarterA Jory
Jun 1, 1980·The American Journal of Surgical Pathology·J L SklarK G Bensch
Sep 1, 1962·Cancer·H HAMPERL

❮ Previous
Next ❯

Citations

Aug 8, 1998·International Urology and Nephrology·Y KubotaK Kawai
Feb 9, 2011·Journal of Endocrinological Investigation·F GuaraldiP Caturegli
Dec 20, 2000·São Paulo Medical Journal = Revista Paulista De Medicina·R T de AquinoV L Capelozzi
Dec 10, 2015·Advances in Anatomic Pathology·Nadja FalkCesar A Moran
Apr 28, 2021·Archivos de bronconeumología·Juan Alcántara-FructuosoAlberto Giménez-Bascuñana

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.