Pulmonary Rehabilitation in Patients with Pulmonary Sarcoidosis: Impact on Exercise Capacity and Fatigue.

Respiration; International Review of Thoracic Diseases
Anita GrongstadAnne Edvardsen

Abstract

There is limited evidence regarding the impact of multidisciplinary pulmonary rehabilitation (PR) on exercise capacity and fatigue in patients with pulmonary sarcoidosis. The aim of this study was to evaluate the impact on exercise capacity and fatigue following PR, and to examine whether baseline fatigue was related to change in peak oxygen uptake (ΔV̇O2peak). Forty-one patients with pulmonary sarcoidosis attending a 4-week inpatient PR program were recruited to this pre-post study. Both maximal exercise capacity, defined as V̇O2peak and measured with a cardiopulmonary exercise test, and fatigue, assessed with the Fatigue Assessment Scale (score 10-50 points), were measured before and after PR. There was a statistically significant improvement in V̇O2peak (1.2 ± 2.3 mL/kg/min, p = 0.002), and fatigue decreased significantly (-1.7 ± 3.9 points, p = 0.009) following PR. Unadjusted linear regression analyses demonstrated that age (B = -0.076, p = 0.017) and baseline fatigue (B = 0.196, p = 0.001) were predictors for change in V̇O2peak, while in adjusted analyses (age, sex, baseline V̇O2peak, baseline fatigue, and diffusion capacity of the lung for carbon monoxide), only baseline fatigue predicted change in V̇O2peak following PR (...Continue Reading

References

Mar 15, 2002·The New England Journal of Medicine·Jonathan MyersJ Edwin Atwood
Jul 2, 2002·American Journal of Respiratory and Critical Care Medicine·UNKNOWN ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories
Jan 14, 2003·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN American College of Chest Physicians
Aug 7, 2004·British Journal of Health Psychology·Jolanda De VriesMarjolein Drent
Sep 2, 2005·The European Respiratory Journal·J WangerG Viegi
Oct 13, 2006·Chest·Helen J MichielsenJolanda De Vries
Jul 13, 2007·Chest·Robert P BaughmanElyse E Lower
May 22, 2009·Current Opinion in Pulmonary Medicine·Willemien P E de KleijnMarjolein Drent
Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Ganesh RaghuUNKNOWN ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis
Jun 28, 2011·Respiratory Medicine·Willemien P E de KleijnMarjolein Drent
Sep 22, 2011·Respiration; International Review of Thoracic Diseases·Benoit WallaertBernard Aguilaniu
Oct 27, 2012·The European Respiratory Journal·Patrick HuppmannKlaus Kenn
Oct 17, 2013·American Journal of Respiratory and Critical Care Medicine·Martijn A SpruitUNKNOWN ATS/ERS Task Force on Pulmonary Rehabilitation
Mar 5, 2014·European Respiratory Review : an Official Journal of the European Respiratory Society·Katerina M AntoniouVenerino Poletti
Oct 7, 2014·The Cochrane Database of Systematic Reviews·Leona DowmanAnne E Holland
Oct 10, 2014·Advances in Experimental Medicine and Biology·D JastrzębskiJ Kozielski
Oct 25, 2014·Respiration; International Review of Thoracic Diseases·Baruch VainshelboimMordechai Reuven Kramer
Jan 31, 2015·Respiration; International Review of Thoracic Diseases·Anne E HollandCatherine J Hill
Aug 20, 2015·Lung·Bert StrookappeMarjolein Drent
Sep 1, 2015·Patient Preference and Adherence·Anastasios KallianosAggeliki Rapti
Oct 11, 2015·The European Respiratory Journal·Martijn A SpruitUNKNOWN CIRO+ Rehabilitation Network
Jun 15, 2016·Respiratory Medicine·Bert StrookappeMarjolein Drent
Aug 11, 2016·Chronic Respiratory Disease·Chris Atkins, Andrew M Wilson
Aug 24, 2016·Expert Review of Respiratory Medicine·Bert StrookappeMarjolein Drent
Feb 6, 2017·Therapeutic Advances in Respiratory Disease·Atsuhito NakazawaAnne E Holland
Jul 19, 2017·Annals of the American Thoracic Society·Pietro Palermo, Ugo Corrà
Oct 27, 2017·Advances in Experimental Medicine and Biology·K PilzakD Jastrzębski
Nov 14, 2017·Respiration; International Review of Thoracic Diseases·Thomas BahmerAnne-Marie Kirsten
Jan 5, 2018·Internal and Emergency Medicine·Elena Bargagli, Antje Prasse
Feb 28, 2018·Respiration; International Review of Thoracic Diseases·Heidrun LingnerKonrad Schultz
Apr 10, 2019·Journal of Clinical Medicine·Anita GrongstadAnne Edvardsen

❮ Previous
Next ❯

Citations

Jun 19, 2021·Pulmonary Therapy·Andrea S MelaniElena Bargagli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.