Pulmonary-renal syndromes: Experience from an Indian Intensive Care Unit

Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
Srinivas RajagopalaSreejith Parameswaran

Abstract

The etiology of patients presenting with pulmonary-renal syndrome (PRS) to Intensive Care Units (ICUs) in India is not previously reported. The aim was to describe the prevalence, etiology, clinical manifestations, and outcomes of PRS in an Indian ICU and identify variables that differentiate immunologic causes of PRS from tropical syndromes presenting with PRS. We conducted a prospective observational study of all patients presenting with PRS over 1-year. Clinical characteristics of patients with "definite PRS" were compared with those with "PRS mimics". We saw 27 patients with "provisional PRS" over the said duration; this included 13 patients with "definite PRS" and 14 with "PRS mimics". The clinical symptoms were similar, but patients with PRS were younger and presented with longer symptom duration. Ninety-two percent of the PRS cohort required mechanical ventilation, 77% required vasopressors and 61.5% required dialysis within 48 h of ICU admission. The etiologic diagnosis of PRS was made after ICU admission in 61.5%. Systemic lupus erythrematosus (54%) was the most common diagnosis. A combination of biopsy and serology was needed in the majority (69%, 9/13). Pulse methylprednisolone (92%) and cyclophosphamide (61.5%) was ...Continue Reading

References

Jul 1, 1992·Journal of Clinical Pathology·J E CrabtreeM S Losowsky
Feb 21, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·O S Bruland, A Pihl
Jan 5, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Hugh GallagherDavid R W Jayne
Nov 7, 2002·Critical Care Clinics·William RodriguezJayarama Guntupalli
Aug 28, 2004·Clinics in Chest Medicine·Harold R Collard, Marvin I Schwarz
Nov 27, 2004·Intensive Care Medicine·Folafoluwa O Odetola, Susan L Bratton
Feb 8, 2005·Critical Care : the Official Journal of the Critical Care Forum·David SempleRichard Venn
Mar 19, 2005·Critical Care : the Official Journal of the Critical Care Forum·David SempleRichard Venn
May 12, 2007·Critical Care : the Official Journal of the Critical Care Forum·Spyros A PapirisCharis Roussos
Sep 5, 2009·Clinical and Experimental Nephrology·Ali A Al bshabsheMahmoud R Hussein
Oct 1, 2009·Arthritis and Rheumatism·Richard A WattsAlex J Macgregor
Jun 21, 2011·Respiratory Medicine·Colm McCabeRaashid Luqmani
Oct 10, 2012·Arthritis and Rheumatism·J C JennetteR A Watts
Jul 1, 2002·Indian Journal of Clinical Biochemistry : IJCB·M R Venukumar, M S Latha
Dec 6, 2012·Current Infectious Disease Reports·Rodger D Macarthur
Jan 26, 2013·Postgraduate Medical Journal·Stephen C WestCharles D Pusey
Oct 3, 2013·BMC Anesthesiology·Patrice BefortKada Klouche
Apr 8, 2014·Reumatología clinica·Marco Ulises Martínez-Martínez, Carlos Abud-Mendoza
Jan 1, 2011·Journal of Surgical Case Reports·Is GregoryK Choji

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Methods Mentioned

BETA
bronchoalveolar
lavage
enzyme-linked
PCR
ELISA
biopsy
biopsies

Software Mentioned

IndMed
SPSS

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