PMID: 2494958Mar 1, 1989Paper

Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies

Annals of the Rheumatic Diseases
R A AshersonG R Hughes

Abstract

Procainamide is the commonest cause of a drug induced lupus syndrome. Long term administration of this compound may induce a variety of immunological abnormalities, including antinuclear antibodies. Uncommonly, 'lupus anticoagulants' have been demonstrated in the absence of other evidence of drug induced lupus. Details of a 67 year old man who developed not only drug induced lupus but also antiphospholipid antibodies which were associated with multiple pulmonary thromboemboli after the administration of procainamide are recorded.

References

Jul 1, 1975·American Journal of Diseases of Children·J J Irias
Aug 1, 1975·Seminars in Arthritis and Rheumatism·S L Lee, P H CHase
Feb 1, 1979·Clinical Immunology and Immunopathology·M BeckerS Ben-Efraim
Aug 1, 1979·Annals of Internal Medicine·M H ZarrabiA O Varma
Mar 1, 1979·Arthritis and Rheumatism·D A McLain, B H Hahn
Jun 1, 1978·The Journal of Allergy and Clinical Immunology·A J ChandrasekharL Barr
Oct 1, 1977·Archives of Internal Medicine·W R BellJ S Wolfson
Apr 1, 1976·Annals of the Rheumatic Diseases·Y LevoM Ben-Bassat
Mar 1, 1975·Clinical Immunology and Immunopathology·A KlajmanS Ben-Efraim
Aug 1, 1975·Annals of the Rheumatic Diseases·M F GraysonR L Markham
Mar 1, 1976·Annals of Internal Medicine·P D UtsingerH G Bluestein
Jan 22, 1988·JAMA : the Journal of the American Medical Association·D A TriplettC A Orr
Feb 1, 1988·Southern Medical Journal·G C LiM S Currie
Jan 1, 1988·Annual Review of Medicine·E N HarrisG R Hughes
Dec 1, 1986·Postgraduate Medical Journal·R A Asherson, E N Harris
Jan 1, 1987·Annals of the Rheumatic Diseases·A E GharaviG R Hughes
Aug 1, 1974·Experimental and Molecular Pathology·J J Lalich, W C Paik
Jul 10, 1969·The New England Journal of Medicine·S E BlomgrenJ H Vaughan
Apr 1, 1967·The American Journal of Medicine·J M Rosin
Nov 1, 1981·Archives of Internal Medicine·R L EdwardsC J Wakem
Sep 1, 1982·American Journal of Hematology·R T Canoso, H S Sise
Oct 1, 1982·Clinical Immunology and Immunopathology·J P PortanovaE M Tan
Dec 1, 1982·Journal of Clinical Psychopharmacology·S McNevin, M MacKay
Feb 1, 1980·Annals of Internal Medicine·J R MuehS I Rapaport
Dec 27, 1962·The New England Journal of Medicine·A T LADD

❮ Previous
Next ❯

Citations

Mar 1, 1996·The Annals of Thoracic Surgery·M T MetzdorffS J Fried
Aug 1, 1996·Annals of the Rheumatic Diseases·D Rosa-ReR Cervera
Feb 17, 2010·Journal of Medical Case Reports·Ashima MakolHouria Hassouna
Dec 14, 2011·Current Rheumatology Reports·Jeffrey S Dlott, Robert A S Roubey
May 25, 2005·Clinics in Geriatric Medicine·G Andres Quiceno, John J Cush
Mar 21, 2007·Rheumatic Diseases Clinics of North America·G Andres Quiceno, John J Cush
Feb 1, 1997·Journal of the American Academy of Dermatology·G T Nahass
Nov 7, 2002·Critical Care Clinics·Rishi RajHerbert P Wiedemann
Sep 1, 1991·The American Journal of Medicine·S Sheikh, J S Seggev
Dec 13, 2006·Lupus·Y LevyY Shoenfeld
Jun 26, 2001·Clinical and Experimental Dermatology·G K Patel, A V Anstey
Mar 23, 1994·Annals of the New York Academy of Sciences·C NiederauT Heintges
Jan 26, 1999·Clinics in Chest Medicine·S MurinR A Matthay

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.