PMID: 9538301Apr 16, 1998Paper

Pulmonary thromboendarterectomy

Heart
Stuart W Jamieson

Abstract

Although PTE is potentially curative for thromboembolic pulmonary hypertension, probably fewer than 1500 of these operations have been performed worldwide. Unquestionably, the disease is under-recognized, and even among cardiac surgeons PTE is considered very hazardous and perhaps of questionable long-term benefit. Our experience does not support this view. There is neither disagreement regarding the poor prognosis of patients with pulmonary hypertension nor the unsatisfactory results of medical treatment for this disease. The only surgical alternative to PTE is lung transplantation. Compared to lung transplantation, PTE offers a lower surgical mortality rate, better long-term survival, and fewer chronic complications. The mortality rate for PTE at our centre is now in the range of 5-7%, with documented sustained functional improvement in survivors. These results clearly favour PTE as the primary treatment for thromboembolic pulmonary hypertension, and physicians should be encouraged to identify patients with this now curable disease.

Citations

Sep 10, 2005·Seminars in Cardiothoracic and Vascular Anesthesia·Gerard R ManeckeStuart W Jamieson
Feb 2, 2008·Arteriosclerosis, Thrombosis, and Vascular Biology·Diana BondermanIrene M Lang
Dec 26, 2015·Journal of Cardiovascular Medicine·Nicola VistariniAndrea Maria D'Armini
Oct 3, 2008·Current Opinion in Cardiology·Irene M Lang, Walter Klepetko
Apr 11, 2007·Circulation·Diana BondermanIrene M Lang
May 31, 2006·Expert Opinion on Pharmacotherapy·Rodney HughesJoanna Pepke-Zaba
Dec 23, 2006·Seminars in Thoracic and Cardiovascular Surgery·Gerard R Manecke
Feb 24, 2009·Revista española de cardiología·Irene M Lang, Walter Klepetko

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