PMID: 2499904Jan 1, 1989Paper

Pulsatile luteinizing hormone release and ovarian steroid levels in female-to-male transsexuals compared to heterosexual women

Psychoneuroendocrinology
T SpinderC W Burger

Abstract

It has been suggested that there is a difference in the interaction between sex steroids and gonadotropin secretion between transsexual and heterosexual women. In this study we tested whether there is a difference in the pulsatile release characteristics of luteinizing hormone (LH) and in ovarian steroid concentrations between 16 female-to-male (f-to-m) transsexuals and eight eugonadal heterosexual women during the early follicular phase of the menstrual cycle. Blood samples for LH determination were collected every 10 min for 7 hr in the transsexual group, and every 10 min for 6 hr in the heterosexual group. There were no significant differences between the transsexual and heterosexual group in mean serum LH concentration (6.9 +/- 2.4 U/l vs. 7.5 +/- 2.6 U/l), mean LH nadir interval (77 +/- 37 min vs. 70 +/- 16 min), and mean LH pulse amplitude (2.9 +/- 1.1 U/l vs. 3.0 +/- 1.1 U/l). Serum estrone, 17-beta-estradiol, testosterone, progesterone and FSH concentrations also did not differ between the two groups. There also was not a higher prevalence of polycystic ovarian disease in our f-to-m transsexual group than in the general population.

References

Jul 1, 1978·The Journal of Clinical Endocrinology and Metabolism·L E SeylerS Reichlin
Mar 1, 1979·Archives of Sexual Behavior·H F Meyer-Bahlburg
Oct 1, 1973·The Journal of Clinical Investigation·R J Santen, C W Bardin
Jul 1, 1983·The Journal of Clinical Endocrinology and Metabolism·M Wiesen, W Futterweit
Mar 1, 1954·Obstetrics and Gynecology·L S McGOOGAN

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Citations

Jan 1, 1990·Psychoneuroendocrinology·L Gooren
Jul 1, 1997·Psychoneuroendocrinology·H A BosinskiR Wille
Mar 19, 2002·The Journal of Steroid Biochemistry and Molecular Biology·Dezhong J Liao, Robert B Dickson
Dec 18, 2003·Clinical Endocrinology·Tasoula TsilchorozidouGerard S Conway
Aug 9, 2008·Orvosi hetilap·Krisztián Kórász, Lajos Simon

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