Pulse-inversion US imaging of testicular ischemia: quantitative and qualitative analyses in a rabbit model

Radiology
Harriet J PaltielLuiz G Freitas-Filho

Abstract

To quantitatively and qualitatively assess perfusion with pulse-inversion (PI) ultrasonography (US) in rabbit model of acute testicular ischemia. Institutional animal care committee approval was obtained. After 35 rabbits underwent unilateral spermatic cord occlusion, testicular Doppler US and contrast material-enhanced PI imaging were performed. Enhancement data yielded perfusion measurements including mean value during the first 10 seconds, mean value over entire recorded replenishment curve, and curve slope during the first 5 seconds. Calculated perfusion ratios were compared with radiolabeled microsphere-derived perfusion ratios. Two readers assessed testicular perfusion as none, possible, or definite and relative perfusion as greater to the right testis than to the left, greater to the left testis than to the right, or as equal to both testes. With kappa statistics, interobserver agreement for all imaging methods was determined. Association between qualitative perfusion categories and radiolabeled microsphere-based perfusion measurements was assessed. Quantitative and qualitative determinations of relative perfusion were compared with radiolabeled microsphere-based measurements. Correlations between calculated and radiolab...Continue Reading

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Citations

Mar 14, 2007·European Radiology·Emilio Quaia
Oct 12, 2010·European Radiology·Emilio Quaia
Jun 3, 2011·European Radiology·Massimo ValentinoLibero Barozzi
Mar 24, 2011·AJR. American Journal of Roentgenology·Michele BertolottoMaria A Cova
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May 16, 2021·Pediatric Radiology·Anush SridharanRyne A Didier

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