Pulse Oximetry Overestimates Oxyhemoglobin in Neonates with Critical Congenital Heart Disease

Neonatology
Daniel MurphyJohn Patrick Cleary

Abstract

Pulse oximetry is a key part of the clinical evaluation and management of neonates with congenital heart defects. In 2011, the US Department of Health and Human Services recommended use of routine pulse oximetry to screen for critical congenital heart disease (CCHD). Current studies suggest pulse oximetry overestimates arterial oxygen saturation in moderately hypoxemic pediatric patients. Based on variable hypoxemia in neonates with CCHD, concern exists that present pulse oximeter technology may overestimate measured oxyhemoglobin. To compare pulse oximetry and oxyhemoglobin values in NICU patients with known CCHD to evaluate the ability of pulse oximetry to reliably predict oxyhemoglobin accounting for potential confounding variables such as heart lesion, saturation range, total hemoglobin concentration, peripheral perfusion, and timing of measurements. This is a single-center retrospective study. Inclusion criteria were AHA-defined CCHD and umbilical artery blood gas-derived oxyhemoglobin with concurrent pulse oximetry recording during hours of life 0-72. Bland-Altman analysis and the concordance correlation coefficient were used to measure the internal consistency (agreement) between the two measurements. 89 patients were ev...Continue Reading

Citations

Nov 9, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yigit S GunerPeter T Yu
Jun 5, 2018·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yigit S GunerDanh V Nguyen
Oct 9, 2019·Journal of Neonatal-perinatal Medicine·J I E Hoffman, B S Hons

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