Pulse wave analysis is a reproducible technique for measuring central blood pressure during hemodynamic perturbations induced by exercise

American Journal of Hypertension
David J HollandJames E Sharman

Abstract

Central blood pressure (BP) and markers of wave reflection (augmentation index; AIx) measured by radial tonometry have prognostic value independent from brachial BP. The measurement of the central waveform is increasingly used during altered hemodynamics, including exercise, but reliability of the test has not been reported under changed loading conditions. This study aimed to test the technique's reproducibility during major hemodynamic perturbations induced by exercise. Radial waveforms were recorded (SphygmoCor) in 28 healthy subjects (aged 53 +/- 11 years) at rest, during submaximal exercise (cycling at 50, 60, and 70% of maximal age-predicted heart rate (HR)) and immediately after maximal treadmill exercise on two occasions separated by 9 +/- 5 days. Data were compared between testing days. Waveforms were calibrated with brachial BP measured using a mercury sphygmomanometer. Pulse pressure amplification (PPAmp) was defined as the ratio of brachial to central pulse pressure. There was very good reproducibility between visits at all exercise intensities for all waveform measures, including AIx, central pulse pressure, and PPAmp (intraclass correlations at 50% exercise were 0.93, 0.89, and 0.89, respectively; P < 0.001). The ...Continue Reading

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Citations

Feb 22, 2013·Journal of Human Hypertension·C A FahsB Fernhall
Dec 7, 2013·American Journal of Hypertension·Jake C ReeveJames E Sharman
Feb 25, 2014·American Journal of Hypertension·Darren T BeckRandy W Braith
Apr 1, 2011·Blood Pressure·Martin G SchultzJames E Sharman
Dec 30, 2014·European Journal of Applied Physiology·Sonja B NikolicJames E Sharman
Mar 8, 2013·American Journal of Hypertension·Martin G SchultzJames E Sharman
Sep 23, 2008·American Journal of Hypertension·Darren P Casey
Sep 2, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·David J HollandThomas H Marwick
Jan 10, 2012·American Journal of Hypertension·Rachel E D ClimieJames E Sharman
Jan 15, 2011·American Journal of Hypertension·Jeffrey S MartinRandy W Braith
Aug 13, 2011·American Journal of Hypertension·Chi Young ShimJong-Won Ha
Aug 3, 2011·The Journal of Clinical Hypertension·Cameron T ColemanJames E Sharman
May 6, 2015·Vascular Medicine·Wesley K LeffertsDenise L Smith
Aug 22, 2014·European Journal of Applied Physiology·A D LaneB Fernhall
Sep 2, 2009·Hypertension·James E SharmanThomas H Marwick
Sep 2, 2009·Hypertension·James E SharmanThomas H Marwick
Jun 21, 2011·Medicine and Science in Sports and Exercise·Julian W SacreJames E Sharman
Aug 24, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Erin J HowdenThomas H Marwick
Oct 1, 2011·European Journal of Clinical Investigation·Martin G SchultzJames E Sharman
Sep 20, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Anders SahlénReidar Winter
Jun 10, 2015·Medicine and Science in Sports and Exercise·Abbi D Lane-CordovaB O Fernhall
Apr 15, 2011·American Journal of Physiology. Heart and Circulatory Physiology·David J HollandJames E Sharman
Oct 1, 2010·Medicine and Science in Sports and Exercise·Martin G SchultzJames E Sharman
Apr 3, 2020·Journal of Applied Physiology·Alexander J RosenbergTracy Baynard
Jun 17, 2020·Clinical and Experimental Hypertension : CHE·Kadir Uğur MertBülent Görenek
Apr 30, 2016·Journal of Hypertension·Weijie LimLee Stoner
Jul 9, 2010·The Journal of Clinical Endocrinology and Metabolism·L K PhillipsJ B Prins
Jan 20, 2019·European Journal of Applied Physiology·Francisco Morales-AcunaAlvaro N Gurovich
Jul 30, 2014·Journal of the Renin-angiotensin-aldosterone System : JRAAS·Peter S LacyBryan Williams
Mar 1, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Rachel E D ClimieJames E Sharman
Nov 16, 2011·Current Hypertension Reports·Michael F O'Rourke, Audrey Adji

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