Pulsed dye laser alone versus its combination with topical ivermectin 1% in treatment of Rosacea: a randomized comparative study

The Journal of Dermatological Treatment
MaiAbdelraouf OsmanMarwa Atef Khalifa

Abstract

Background: While the etiology of rosacea is multifactorial, it is not surprising that treatment has been controversial. Pulsed dye laser (PDL) has been successfully used to treat vascular components of rosacea. Ivermectin 1% cream is an emerging treatment of rosacea.Objective: To provide a comprehensive clinical and dermatoscopic comparative study between the efficacy and safety of pulsed dye laser alone versus its combination with topical ivermectin 1% in the treatment of rosacea.Materials and methods: Thirty Patients were randomly divided into two groups. Group A (n = 15) treated with 585 nm PDL, and group B (n = 15) treated with 585 nm PDL and topical ivermectin 1% cream. All patients received four laser treatments with a 4-week interval. The efficacy of treatment was assessed by photographs and dermoscopic photomicrographs at baseline and 3 months after the final treatment. The patient's level of satisfaction was also recorded.Results: At the 3-month follow-up, group B induced better clinical improvement than group A. However, this difference was not significant. No serious adverse events were observed in either treatment group.Conclusion: This study supports the efficacy of PDL treatment for patients with rosacea. PDL cou...Continue Reading

References

May 18, 2004·British Journal of Plastic Surgery·S T TanJ R Armstrong
Sep 1, 2004·Journal of the American Academy of Dermatology·Glen H CrawfordWilliam D James
Feb 25, 2005·The New England Journal of Medicine·Frank C Powell
Apr 17, 2008·Lasers in Surgery and Medicine·Eric F Bernstein, Albert Kligman
Jul 9, 2009·Indian Journal of Dermatology, Venereology and Leprology·Alireza Keshtcar-JafariSiavash Toosi
Jun 24, 2011·Clinical Psychology & Psychotherapy·Daphne Su, Peter D Drummond
Oct 25, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·F M N Forton
Apr 5, 2012·Internal Medicine Journal·C Macdonald, T Cawood
Mar 16, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·A LallasI Zalaudek
Jul 25, 2013·International Journal of Dermatology·Aimilios LallasIris Zalaudek
Nov 27, 2014·The Journal of Dermatological Treatment·Manal Abokwidir, Alan B Fleischer
Apr 22, 2015·Journal of the American Academy of Dermatology·Aimee M TwoTissa R Hata
Mar 19, 2016·The Nurse Practitioner·Daria B Napierkowski
Apr 7, 2016·Clinical, Cosmetic and Investigational Dermatology·Leah A CardwellSteven R Feldman
Jun 28, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·M SchallerC Borelli
Apr 11, 2018·Lasers in Surgery and Medicine·Eric F BernsteinChristopher J Jones

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Related Papers

Dermatology Online Journal
Marta Mendieta Eckert, Nerea Landa Gundin
Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology
Molly HirtRonda S Farah
Expert Opinion on Pharmacotherapy
Dev R SahniSarah Taylor
American Journal of Clinical Dermatology
Emma D Deeks
© 2021 Meta ULC. All rights reserved