Pulsed electric field inactivation of microorganisms: from fundamental biophysics to synergistic treatments

Applied Microbiology and Biotechnology
Allen L Garner

Abstract

The growth of antibiotic resistant microorganisms and the increasing demand for nonthermal antimicrobial treatment in the food and beverage industry motivates research into alternative inactivation methods. Pulsed electric fields (PEFs) provide an athermal method for inactivating microorganisms by creating nanometer-sized membrane pores in microorganisms, inducing cell death when the PEF duration and intensity are sufficient such that the pores cannot reseal after the PEFs through a process referred to as irreversible electroporation. While PEF inactivation has been studied for several decades, recent studies have focused on extending the technique to various liquids in the food industry and optimizing microorganism inactivation while minimizing adverse effects to the treated sample. This minireview will assess the biophysical mechanisms and theory of PEF-induced cellular interactions and summarize recent advances in applying this technology for microorganism inactivation alone and synergistically in combination with other technologies, including temperature, pressure, natural ingredients, and pharmaceuticals.

References

Aug 1, 1968·Biochimica Et Biophysica Acta·A J Sale, W A Hamilton
Jan 7, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·R P Joshi, K H Schoenbach
Jul 21, 2004·BMC Biochemistry·D Peter Tieleman
Jul 13, 2006·IEEE Transactions on Bio-medical Engineering·Jon F EddBoris Rubinsky
Aug 26, 2006·Medical & Biological Engineering & Computing·C ChenJ A Evans
Oct 10, 2006·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Zlatko VasilkoskiJames C Weaver
Oct 21, 2006·BMC Cell Biology·P Thomas VernierMartin A Gundersen
Aug 21, 2007·Biochemical and Biophysical Research Communications·Allen L GarnerKarl H Schoenbach
Aug 30, 2008·Critical Reviews in Food Science and Nutrition·Jonathan Mosqueda-MelgarOlga Martín-Belloso
Sep 4, 2008·Physical Review Letters·Fernando BresmeSigne Kjelstrup
Mar 5, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Q Hu, R P Joshi
May 1, 2010·The Journal of Physical Chemistry. B·M Laura FernándezRamon Reigada
Feb 19, 2011·International Journal of Food Microbiology·S MonfortI Alvarez
Feb 18, 2012·Technology in Cancer Research & Treatment·Alex Golberg, Boris Rubinsky
May 31, 2012·The Journal of Membrane Biology·Lucie Delemotte, Mounir Tarek
Sep 8, 2012·Biochimica Et Biophysica Acta·Jianbo LiHao Lin
Jun 20, 2013·The Journal of Membrane Biology·Andraž PolakMounir Tarek
Dec 18, 2013·Biochemical and Biophysical Research Communications·Bennett L IbeyAndrei G Pakhomov
Sep 23, 2014·Nanomedicine : Nanotechnology, Biology, and Medicine·Aimee E KrauszAdam J Friedman
Nov 13, 2014·IEEE Transactions on Bio-medical Engineering·Chunlan JiangJohn Bischof
Nov 19, 2015·Expert Opinion on Drug Delivery·Laure LambrichtGaëlle Vandermeulen
Nov 13, 2012·Journal of Chemical Theory and Computation·Thomas J PiggotSyma Khalid
Mar 8, 2016·Bioelectrochemistry·Tina Batista NapotnikDamijan Miklavčič
Aug 27, 2016·IEEE Transactions on Plasma Science·Ross A PetrellaShu Xiao
Sep 13, 2016·Journal of Infection and Public Health·Marianne FrieriAnthony Boutin
Apr 23, 2017·Biochimica Et Biophysica Acta. Biomembranes·Caterina MerlaP Thomas Vernier
Nov 18, 2017·Bioelectrochemistry·Jeffrey L MoranCullen R Buie
Mar 5, 2018·Journal of Applied Microbiology·J Van ImpeA Režek Jambrak
Apr 22, 2018·Letters in Applied Microbiology·M KoremA E Moses
Jul 11, 2018·Technology in Cancer Research & Treatment·Ute ProbstPhilipp Wiggermann
Jul 19, 2018·Applied Microbiology and Biotechnology·Anand VadlamaniAllen L Garner

❮ Previous
Next ❯

Citations

Jan 23, 2020·Applied Microbiology and Biotechnology·Ram Anand VadlamaniAllen L Garner
Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Hongchao ZhangStratton T Wimsatt
Jul 4, 2021·Bioelectrochemistry·B G Rodríguez-MéndezD Alcántara-Díaz
Nov 5, 2021·Frontiers in Microbiology·Žana LovšinTadej Kotnik

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis
MDS
flow cytometry

Software Mentioned

MDS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Critical Reviews in Food Science and Nutrition
J Raso, G V Barbosa-Cánovas
Heart Rhythm : the Official Journal of the Heart Rhythm Society
Elad MaorSuraj Kapa
Technology in Cancer Research & Treatment
Alex T EsserJames C Weaver
© 2021 Meta ULC. All rights reserved