Pump failure death and sudden cardiac death in patients with cardiac dysfunction: a search for prognostic predictive factors--a long-term follow-up study

Journal of cardiology
Hiroki UsukuHisao Ogawa

Abstract

There have been few reports that have analyzed the predictive factors for heart failure death, which is sub-divided into pump failure death and sudden cardiac death, in the long term. We followed 186 consecutive patients with myocardial infarction (MI) and 115 consecutive patients with non-ischemic heart failure (NIHF) during 73+/-3 months. In the MI group, 26 died from pump failure and 12 died from sudden cardiac death. In the NIHF group, 21 died from pump failure and 9 died from sudden cardiac death. Multivariate analysis revealed that the log B-type natriuretic peptide (BNP) was an independent predictor for pump failure death in both groups. In the MI group, the estimated glomerular filtration rate (eGFR) was an independent predictor for sudden cardiac death. Kaplan-Meier analysis revealed that a high BNP level was a risk factor for pump failure death in either MI or NIHF patients. On the other hand, the sudden cardiac death rate was significantly higher in the MI patients with low eGFR than in those with high eGFR. The plasma BNP level is an independent predictor for pump failure death in both MI and NIHF patients. The eGFR is an independent predictor for sudden cardiac death in MI patients.

References

Jan 1, 1990·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·G MallE Ritz
Dec 1, 1987·British Heart Journal·J G ClelandI Ford
Mar 3, 1988·Nature·T SudohH Matsuo
Oct 23, 1997·American Journal of Human Genetics·P D'AdamoD Toniolo
Apr 29, 1998·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M A MoralesQ Maggiore
Dec 7, 2000·The New England Journal of Medicine·M KamisagoC E Seidman
May 16, 2003·The New England Journal of Medicine·Mariell Jessup, Susan Brozena
Sep 24, 2004·The New England Journal of Medicine·Alan S GoChi-yuan Hsu
Aug 9, 2006·The American Journal of Cardiology·Ilan GoldenbergUNKNOWN Multicenter Automatic Defibrillator Implantation Trial-II Investigators
Nov 27, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Enyu ImaiSeiichi Matsuo

❮ Previous
Next ❯

Citations

Dec 22, 2010·Internal Medicine·Terumasa InoueMichihiro Yoshimura
Aug 5, 2015·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Antonio Carlos Pereira-BarrettoDenilson Campos de Albuquerque
Apr 25, 2018·Circulation·Bradley S MarinoUNKNOWN American Heart Association Congenital Cardiac Defects Committee of the Council on Cardiovascular Disease in the Young; Counc
Jan 18, 2012·Current Opinion in Cardiology·Kathleen E Simpson, Charles E Canter

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.